نتایج جستجو برای: poly lactic acid pla

تعداد نتایج: 816084  

Background: Adapting controlled release technologies to the delivery of DNA has the great potential to overcome extracellular barriers that limit gene delivery. This study investigates the effect of different mass ratio of PLA: PEG in the various tri block poly (lactic acid)-poly (ethylene glycol) - Poly (lactic acid) copolymer (PLA-PEG-PLA) on the properties of the resulting nanoparticles. Me...

2011
Hideto Tsuji Takehiko Eto Yuzuru Sakamoto

Non-substituted racemic poly(DL-lactic acid) (PLA) and substituted racemic poly(DL-lactic acid)s or poly(DL-2-hydroxyalkanoic acid)s with different side-chain lengths, i.e., poly(DL-2-hydroxybutanoic acid) (PBA), poly(DL-2-hydroxyhexanoic acid) (PHA), and poly(DL-2-hydroxydecanoic acid) (PDA) were synthesized by acid-catalyzed polycondensation of DL-lactic acid (LA), DL-2-hydroxybutanoic acid (...

Numerous Scientists have discovered the procedure of nanotechnology, explicitlynanofibers, asdrug delivery systems for transdermal uses. Nanofibers canbe used to deliver drugs and are capable of controlled release for a continued periodof time. Poly (Lactic Acid) (PLA) is the lastly interesting employed synthetic polymer in biomedical application owing to its well categorized biodegradable prop...

Journal: :International journal of pharmaceutics 2011
Nobuo Umeki Takayuki Sato Masahiro Harada Junko Takeda Shuji Saito Yasunori Iwao Shigeru Itai

To achieve sustained release of 3-ethyl-4-(4-methylisoxazol-5-yl)-5-(methylthio) thiophene-2-carboxamide (BFB0261), a new potent osteogenic compound for treating bone disorders, we prepared film formulations containing BFB0261 and the following newly synthesized biodegradable polymers by a solvent casting technique: poly(D,L-lactic acid) (PLA), poly(D,L-lactic acid-co-glycolic acid) (PLGA), pol...

2013

Poly (lactic acid) (PLA) is biodegradable, melt processable and environmentally benign aliphatic polyester produced from the fermentation of natural renewable resources like corn, sugar and vegetable. The comparative analysis of the effect of time of heatsetting and wet processing from this research showed that PLA exhibited good textile properties for versatile end applications. This research ...

Journal: :پژوهش های علوم و صنایع غذایی ایران 0
hadi almasi babak ghanbarzadeh jalal dehghannia ali akbar entezami asgharr khosrowshahi asl

fatty acid modified cellulose nanofibers (mcnfs) and tbhq antioxidant were added to poly(lactic acid) (pla) film. the combined effects of the mcnfs and tbhq on the morphological, thermal, mechanical and barrier properties of pla film were analyzed. the morphology of fracture surfaces evaluated by field emission scanning electron microscopy (fe-sem). xrd results showed that the crystallinity of ...

Objective(s): Nowadays, tendency to use green materials can reduce environmental pollution and plastic waste. Poly (lactic Acid) PLA is one of the natural biodegradable polymers mainly used in the production of bioplastics for packaging which is made of non-toxic compounds and is easily biodegradable. In this research, the effect of 1, 3 and 5% nanocomposite zinc oxide on the morphological, mec...

Journal: :Macromolecular bioscience 2005
Hideto Tsuji

Poly(lactide)s [i.e. poly(lactic acid) (PLA)] and lactide copolymers are biodegradable, compostable, producible from renewable resources, and nontoxic to the human body and the environment. They have been used as biomedical materials for tissue regeneration, matrices for drug delivery systems, and alternatives for commercial polymeric materials to reduce the impact on the environment. Since ste...

2011
Pegah Dadras Seyed Mostafa Khezri Rasoul Dinarvand

The aim of this study was to develop a new polymeric gel that used as a contraceptive system.Polymeric gel has been studied extensively for drug delivery systems. In this article, thermalsensitive poly (DL-lactic acid)-poly (ethylene glycol) poly (DL-lactic acid) (PLA-PEG-PLA) hydrogel was used as an implantable contraceptive system.Aqueous solution of this copolymer fromed a free flowing so at...

2017
Hideto Tsuji Soma Noda Takayuki Kimura Tadashi Sobue Yuki Arakawa

D-configured poly(D-lactic acid) (D-PLA) and poly(D-2-hydroxy-3-methylbutanoic acid) (D-P2H3MB) crystallized separately into their homo-crystallites when crystallized by precipitation or solvent evaporation, whereas incorporation of L-configured poly(L-2-hydroxybutanoic acid) (L-P2HB) in D-configured D-PLA and D-P2H3MB induced co-crystallization or ternary stereocomplex formation between D-conf...

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