background: malaria is a major cause of morbidity and mortality in nepal. the magnitude of malaria across the country is alarming and varies with location. therefore, the present study aimed to model malaria incidence rates during 1998 to 2009 in nepal. methods: data for the study were obtained from health management information system (hmis), ministry of public health. a negative binomial mode...

‎Multivariate normal-Poisson model has been recently introduced as a special case of normal stable Tweedie models‎. ‎The model is composed of a univariate Poisson variable‎, ‎and the remaining variables given the Poisson one are independent Gaussian variables with variance the value of the Poisson component‎. ‎Two characterizations of this model are shown‎, ‎...

ion channels are naturally occurring pores through the proteins that regulate the passage of ions and thus maintain the concentration of ions inside and outside the cell. the ion channels control many physiological functions and they can show selectivity for a specific ion. ion channels are mostly observed in nerve cells and muscle cells. the influx of ions into cells can be regulated by a gate...

scott and szewczyk in technometrics, 2001, have introduced a similarity measure for twodensities f1 and f2 , by1, 21 21 1 2 2( , ), ,f fsim f ff f f f< >=< >< >wheref1, f2 f1(x, θ1)f2(x, θ2)dx.+∞−∞< >=∫sim(f1, f2) has some appropriate properties that can be suitable measures for the similarity of f1 and f2 .however, due to some restrictions on the value of parameters and the kind of densities, ...

The Liu estimator has consistently been demonstrated to be an attractive shrinkage method for reducing the effects of multicollinearity. The Poisson regression model is a well-known model in applications when the response variable consists of count data. However, it is known that multicollinearity negatively affects the variance of the maximum likelihood estimator (MLE) of the Poisson regressio...

The classical integer valued first-order autoregressive (INA- R(1)) model has been defined on the basis of Poisson innovations. This model has Poisson marginal distribution and is suitable for modeling equidispersed count data. In this paper, we introduce an modification of the INAR(1) model with geometric innovations (INARG(1)) for model- ing overdispersed count data. We discuss some structu...

background & aim: in the survival data with long-term survivors the event has not occurred for all the patients despite long-term follow-up, so the survival time for a certain percent is censored at the  end  of the  study.  mixture  cure  model  was  introduced  by boag,  1949  for  reaching  a  more efficient analysis of this set of data. because of some disadvantages of this model non-mixtur...

the use of stokes boundary values problems for the determination of the geoid requires that gravity anomalies (as boundary values) are known on geoid (as boundary). while, the gravity observations are measured on the earth&apos;s surface, to obtain boundary data, the surface gravity anomalies does are downward from the terrain onto geoid. for downward continuation (dwc) of surface gravity anoma...