background and objectives: pneumocystis jirovecii pneumonia (pjp) is a chronic fungal infection that caused by p. ji- rovecii . disease is more prevalent among the hiv-infected patients. the colonization of pneumocystis in human respiratory system is associated with the airway inflammation and obstruction. the current study was conducted to identify the preva- lence of p. jirovecii among the pa...

pneumocystis jirovecii causes pneumocystis pneumonia (pcp) in immunocompromised patients with a high rate of morbidity and mortality. colonization with this fungus may stimulate pulmonary inflammation or lead to pcp in susceptible patients. the epidemiology of this infection and routs of its transmission has poorly studied in iran. we examined pneumosystis colonization in patients with various ...

Background and Purpose: Pneumocystis pneumonia, caused by Pneumocystis jirovecii, is a fatal disease threatening patients with AIDS or immunosuppression. Assessment of colonization in these patients is of great significance, since it can lead to severe pulmonary disorders. Considering the scarcity of published reports on Pneumocystis jirovecii isolates from patients in Mashhad, Iran, we aimed t...

background and purpose: pneumocystis pneumonia, caused by pneumocystis jirovecii, is a fatal disease threatening patients with aids or immunosuppression. assessment of colonization in these patients is of great significance, since it can lead to severe pulmonary disorders. considering the scarcity of published reports on pneumocystis jirovecii isolates from patients in mashhad, iran, we aimed t...

BACKGROUND In patients with chronic respiratory disease, Pneumocystis jirovecii (P. jirovecii) colonization is observed, and may influence disease progression and systemic inflammation. Pneumocystis pneumonia causes interstitial changes, so making a diagnosis of PCP in patients who have interstitial pneumonia (IP) with P. jirovecii colonization is sometimes difficult based on radiography. MET...

BACKGROUND Airborne transmission of Pneumocystis has been demonstrated in animal models and is highly probable in humans. However, information concerning burdens of Pneumocystis jirovecii (human-derived Pneumocystis) in exhaled air from infected patients is lacking. Our objective is to evaluate P. jirovecii air diffusion in patients with Pneumocystis pneumonia. METHODS Patients admitted with ...

OBJECTIVE To assess the predisposing immunocompromised states, administration of pneumocystis jirovecii pneumonia prophylaxis, the disease course and outcomes of patients with pneumocystis jirovecii pneumonia. METHODS The retrospective study was conducted at the Aga Khan University Hospital in Karachi. The medical records of patients diagnosed with pneumocystis jirovecii pneumonia from Januar...

Methotrexate has immunosuppressive effects and is administered for refractory chronic urticaria. We present a case of Pneumocystis jirovecii pneumonia in a patient with refractory chronic urticaria managed by low-dose weekly methotrexate treatment (total cumulative dose 195mg). Our study highlights the importance of providing prompt diagnosis and treatment of Pneumocystis jirovecii pneumonia in...

BACKGROUND Pneumocystis jirovecii, formerly named Pneumocystis carinii, is one of the most common opportunistic infections in human immunodeficiency virus (HIV)-infected patients. CASE PRESENTATIONS We encountered two cases of spontaneous pneumomediastinum with subcutaneous emphysema in HIV-infected patients being treated for Pneumocystis jirovecii pneumonia with trimethoprim/sulfamethoxazole...