Background and Objective: Pneumocystis pneumonia (PCP) has been historically the most prevalent opportunisticinfection in patients infected with the human immunodeficiencyvirus. Culture of the organism has not been faced with suitable success in artificial media, while various results have been reported for cell culture media. The aim of this study was proliferation of Pneumocystis carin...

background and objective: pneumocystis pneumonia (pcp) has been historically the most prevalent opportunisticinfection in patients infected with the human immunodeficiencyvirus. culture of the organism has not been faced with suitable success in artificial media, while various results have been reported for cell culture media. the aim of this study was proliferation of pneumocystis carinii on t...

The rat model of Pneumocystis carinii pneumonia is frequently used to study human P. carinii infection, but there are many differences between the rat and human infections. We studied naturally acquired P. carinii in wild rats to examine the relevance of the rat model for human infection. P. carinii DNA was detected in 47 of 51 wild rats and in 10 of 12 nonimmunosuppressed laboratory rats. Evid...

This study reports on a first case of granulomatous Pneumocystis carinii pneumonia (PCP) in a human immunodeficiency virus-negative patient with antineutrophil cytoplasmic antibody-positive Wegener's granulomatosis whilst receiving immunosuppressive treatment. The patient presented with diffuse alveolar haemorrhage, pauci-immune rapid progressive glomerulonephritis and leukocytoclastic vasculit...

The genus Pneumocystis contains a family of fungal organisms that infect a wide variety of mammalian species. Although it is a cause of pneumonia in immunocompromised hosts, recent evidence suggests that these organisms colonize nonimmunosuppressed hosts. Detection of cryptic colonization with Pneumocystis becomes important in animal studies when infection-free animals are necessary. Provocatio...

An immunologically deficient patient had two large nodular densities on the chest x-ray film. On autopsy, large solid accumulations and diffuse pneumonitis with Pneumocystis carinii were found. This represents an unusual manifestation of Pneumocystis carinii.

background: pneumocystis carinii is one of opportunistic organisms especially in immuno-compromised patients. for years, diagnosis of pneumocystis pneumonia (pcp) has relied on microscopic visualization of organism in specimens obtained from the lung either by bronchoalveolar lavage (bal) or by induction of sputum, but failed to provide efficient diagnosis. the aim of this study was to compare ...

the present study was carried out for evaluation of calcoflour white staining (cws) as a rapid method for detection of pneumocystis carinii in respiratory specimens of rats as an animal model for human infection. a total of 35 spraque – dawley rats were divided into two groups. group1 (20 rats) received increasing doses of dexamethasone subcutaneously, and group 2(15 rats)as control group that ...

To better understand the role of immunocompetent hosts in the diffusion of Pneumocystis in the environment, airborne shedding of Pneumocystis carinii in the surrounding air of experimentally infected Sprague Dawley rats was quantified by means of a real-time PCR assay, in parallel with the kinetics of P. carinii loads in lungs and specific serum antibody titres. Pneumocystis-free Sprague Dawley...