itp is an autoimmune blood disorder in which platelet destruction is mediated by anti-platelet antibodies. the mechanisms of anti-platelet antibodies development are still a little known. the rate of some bacterial or viral agents in cause of itp is well known. recently, some study proposed that h pylori infection may be associated with itp and h pylori eradication can improves platelet counts ...

Background & Aims: Recent studies have shown that thrombocytopenia (TP) is associated with poor outcomes in patients with pneumonia, burns, and H1N1 influenza. The aim of this study is to determine the impact of platelet count trends and TP on mortality in intensive care unit (ICU) patients. Materials & Methods: TP was defined as <150,000 platelets/ml. In this study, 300 patients who had been ...

background nonalcoholic fatty liver disease has become a worldwide challenge. liver biopsy remains the single most reliable approach to determine the severity of this disease. as patients with nonalcoholic fatty liver disease require close follow-up, performing this invasive method repeatedly seems impractical; therefore, designing a noninvasive system to follow up patients has become a common ...

conclusions helicobacter pylori infection has a significant effect on platelet count in patients with citp and h. pylori eradication therapy should be considered as an important factor in platelet count recovery in citp patients. results from a total of 23 patients with citp, 43% (10) of the cases were h. pylori positive and after eradication therapy, eight patients (80%) were successfully trea...

BACKGROUND Non-reactive platelet counts elevation occurs mainly in myeloproliferative disorders (MPDs), which have been reported to be closely associated with JAK2 V617F mutation. Complete blood cell count (CBC) is essential in diagnosis of MPDs, however, the impact of JAK2 V617F mutation on the patients' hemogram variation remains not clear. METHODS JAK2 V617F mutation was detected by allele...

the prevalence of helicobacter pylori infection and the effect of its eradication on platelet count in 95 iranian patients with chronic refractory autoimmune thrombocytopenic purpura (critp) was investigated. 69 of 95 patients were infected with h.pylori (72.6%). h.pylori eradication was obtained in 69 infected critp pa tients who were not in remission and had platelet count below 100×109 at th...

Recent studies have shown that long-term hypoxia causes decreased platelet counts in mice and short-term hypoxia increased platelet counts. In an attempt to explain the mechanism that increases platelet counts of mice after exposure to short-term hypoxia, we measured platelet counts, total circulating platelet counts (TCPC), total circulating platelet masses (TCPM), percentages of 35S incorpora...