homocysteine thiolactone was demonstrated to inhibit the growth of 10–12-day-old chicken embryo cardiac tissue explants at 7 × 10−9 −1 × 10−3 m concentrations in a dose-dependent manner. the maximal cardiotoxic effect of homocysteine thiolactone was detected at 1 × 10−3 m, which corresponds to severe hyperhomocysteinemia. the results of experiments on culturing of cardiac tissue explants in the...
