نتایج جستجو برای: pla2 antigen

تعداد نتایج: 201520  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1994
H Gomi Y Tagaya T Nakano T Mikayama K Ishizaka

We obtained human T-cell hybridomas that are specific for bee venom phospholipase A2 (PLA2) and constitutively secrete glycosylation inhibiting factor (GIF). Upon crosslinking of CD3, the hybridoma produced GIF having affinity for PLA2. When affinity-purified PLA2-binding GIF was used as an immunogen, monoclonal antibodies specific for the antigen-binding GIF were obtained. Monoclonal antibody ...

Journal: :nephro-urology monthly 0
mohammadreza ardalan nephrology department, tabriz university of medical sciences, ir iran; }iroopnwo~oostmtuvumont husoskloiwe~s{u{eovcmedical sciences, tabriz, ir iran. 2) mario negriinstitute of pharmacological research, italy +98-4113344339, [email protected]; }iroopnwo~oostmtuvumont husoskloiwe~s{u{eovcmedical sciences, tabriz, ir iran. 2) mario negriinstitute of pharmacological research, italy +98-4113344339, [email protected]

introduction idiopathic membranous nephropathy (mn) is a common cause of adult nephrotic syndrome. recently, m-type phospholipase a2 receptor (pla2-r) has been discovered as the main podocyte antigen in the pathogenesis of idiopathic mn. materials and methods in this mini review, the author searched english-language medline for the terms “membranous nephropathy”, “rituximab”, and “phospholipase...

Journal: :فیض 0
بتول پورقیصری batool pourgheysari pathology and hematology department, shahrekord university of medical sciences, shahrekord, i. r. iran.شهرکرد، دانشگاه علوم پزشکی شهرکرد، گروه پاتولوژی عفت فرخی efat farrokhi مجتبی ساعدی mojtaba saedi

background: inherited thrombophilic gene polymorphisms have been related to the pathogenesis of venous thromboembolism and its outcomes. considering the scarcity of data on the frequency of the thrombophilic gene polymorphisms in iranian populations, the aim of this study was to assess such polymorphisms in healthy individuals. materials and methods: this cross-sectional study was performed on ...

2009
Takeki Suzuki Russell Tracy Jeanenne J Nelson Bruce M. Psaty Curt Furberg

Background: Inflammation may be an etiologic factor in congestive heart failure (CHF). Lipoprotein associated phospholipase A2 (Lp-PLA2) is an inflammation marker associated with vascular risk. One previous study showed an association of Lp-PLA2 activity with CHF risk, but there were only 94 CHF cases and Lp-PLA2 antigen, which is available clinically in the US, was not measured. Methods and Re...

روحی بروجنی, حمید, هاشمی نیا, علی, پورقیصری, بتول ,

  B. Pourgheysari[1][2], A. Hasheminia[3], H. Rouhi-Boroujeni3   Received: 20/02/2014 Sent for Revision: 22/01/2014 Received Revised Manuscript: 09/10/2012 Accepted: 28/07/2012   Background and Objective: Venous thromboembolism (VTE) is one of the main causes of mortality in different human communities. Factor V Leiden, MTHFR C677T polymorphism and PLA2 polymorphism of platele...

Journal: :Journal of the American College of Cardiology 2000
A Kastrati W Koch M Gawaz J Mehilli C Böttiger K Schömig N von Beckerath A Schömig

OBJECTIVE We designed this prospective study to test the hypothesis that platelet antigen (PlA) polymorphism of glycoprotein (GP) IIIa is associated with an increased risk for adverse events after coronary stent placement. BACKGROUND Platelets play a central role in arterial thrombosis. The PlA polymorphism of GP IIIa, a constituent of the fibrinogen receptor, may influence the platelet funct...

2012
Mohammadreza Ardalan

INTRODUCTION Idiopathic Membranous Nephropathy (MN) is a common cause of adult nephrotic syndrome. Recently, M-type phospholipase A2 receptor (PLA2-R) has been discovered as the main podocyte antigen in the pathogenesis of idiopathic MN. MATERIALS AND METHODS In this mini review, the author searched English-language MEDLINE for the terms "membranous nephropathy", "rituximab", and "phospholipa...

2014

Two recombinant antigens (P22U and PLA2), cloned in a L4 Dirofilaria immitis cDNA library, were analyzed by Western-blot and ELISA to investigate their characteristics for the diagnosis of human dirofilariosis. P22U seems related to a Di22 native antigen useful for the diagnosis of pulmonary dirofilariosis, but it is unspecifically recognized by sera from patients with different parasitic and n...

2015
Dae Yong Kim Jai Youl Ro Chang Ho Lee

BACKGROUND Antiallergic effect of 20(S)-protopanaxatriol (PPT), an intestinal metabolite of ginseng saponins, was investigated in guinea pig lung mast cells and mouse bone marrow-derived mast cells activated by a specific antigen/antibody reaction. METHODS Increasing concentrations of PPT were pretreated 5 min prior to antigen stimulation, and various inflammatory mediator releases and their ...

Journal: :avicenna journal of phytomedicine 0
mohammad hossein boskabady neurogenic inflammation research centre and department of physiology, school of medicine, mashhad university of medical sciences, mashhad, iran sedigheh jalali department of biology, payam noor university, 19395-4697 tehran, iran negin yahyazadeh neurogenic inflammation research centre and department of physiology, school of medicine, mashhad university of medical sciences, mashhad, iran mostafa boskabady neurogenic inflammation research centre and department of physiology, school of medicine, mashhad university of medical sciences, mashhad, iran

objective: pharmacological effects of carvacrol such as its anti-inflammatory activities have been shows. in this study the effects of carvacrol on serum levels of total protein (tp), phospholipase a2 (pla2) and histamine in sensitized guinea pigs was evaluated. materials and methods: sensitized guinea pigs were given drinking water alone (group s), drinking water containing three concentration...

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