platanus acerifolia, london plane tree, a significant source of airborne allergens, is widely grown in shanghai and other cities in china. in recent decades, little has been known regarding the influence of the allergens on sensitizing the population in the shanghai area. the aims of this study were to purify and characterize the two major allergens and to confirm the immunological activities o...

In view of the important oncogenic action of phospholipase A(2)(PLA(2)) we investigated PLA(2) transcripts in human meningiomas. Real-time PCR was used to investigate PLA(2) transcripts in 26 human meningioma tumors. Results indicated that three Ca(2+)-dependent high molecular weight PLA(2) (PLA(2)-IVA, PLA(2)-IVB, PLA(2)-IVC), one Ca(2+)-independent high molecular weight PLA(2) (PLA(2)-VI) and...

statement of the problem: recently allogenic mesenchymal stem cells are proposed to have multipotential progenitor cell capabilities to differentiate into cementoblasts, osteoblasts, and periodontal ligament fibroblasts. purpose: the aim of the present study was to compare the efficacy of human umbilical stem cells cultured on polylactic acid (pla), polyglycolic acid (pga) membrane with pla/pga...

BACKGROUND Phospholipase A(2) (PLA(2)) is involved in regulating biosynthesis of arachidonic acid and its metabolites. There are three major structurally different forms of PLA(2): group I, also called pancreatic PLA(2) (PLA(2)-I); group II, referred to as secretory non-pancreatic or synovial or platelet PLA(2) (PLA(2)-II); group IV, referred to as cytosolic PLA(2) (PLA(2)-IV). AIMS To examin...

BACKGROUND Recent clinical studies showed that lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is a predictor for incident atherosclerotic disease. We have previously shown that among the LDL subfractions, Lp-PLA(2) activity is preferentially associated with the atherogenic small, dense (sdLDL) particles in vitro. We investigated whether Lp-PLA(2) could be a marker of sdLDL in human plasm...

PEG–PLA hydrogels were prepared by stereocomplexation of poly(lactide) (PLA) blocks of opposite chirality. Gelation occurred upon mixing aqueous solutions of both enantiomers of PEG6500–(PLA)2, PEG12500–(PLA)2 and PEG21800–(PLA)8 block copolymers. Stereocomplexed hydrogels from PEG6500–(PLA)2 polymers were found to be stable up to ~37 8C, while those from PEG12500–(PLA)2 and PEG21800–(PLA)8 blo...

Subject codes: [108] Other myocardial biology [145] Genetically altered mice, [151] Ischemic biology-basic studies In November 2013, the average time from submission to first decision for all original research papers submitted to Circulation Research was 14.6 days. ABSTRACT Rationale: Recent evidence indicates that the biological effects of secretory phospholipase A 2 s (sPLA 2) cannot be fully...

Tri-block poly (lactide) poly(ethylene glycol) poly(lactide) (PLA–PEG–PLA) copolymers are among the most attractive nano-carriers for gene delivery into mammalian cells, due to their biocompatibility and biodegradability properties. However, the low efficiency of the gene delivery by these copolymers is an obstacle to gene therapy. Here, we have investigated nanoparticles formulated using the p...

Tri-block poly (lactide) poly(ethylene glycol) poly(lactide) (PLA–PEG–PLA) copolymers are among the most attractive nano-carriers for gene delivery into mammalian cells, due to their biocompatibility and biodegradability properties. However, the low efficiency of the gene delivery by these copolymers is an obstacle to gene therapy. Here, we have investigated nanoparticles formulated using the p...