purpose: to report two patients with keratoconus who underwent regrafting to correct anisometropia and high astigmatism after penetrating keratoplasty. patients and findings: the first case is a 34-year-old man with keratoconus who had undergone penetrating keratoplasty. the sutures were removed 6 months postoperatively that led to high hyperopia. regraft was performed considering vitreous leng...

purpose : to compare outcomes of penetrating keratoplasty (pk) and deep anterior lamellar keratoplasty (dalk) in keratoconic eyes in a university teaching hospital setting methods : in this longitudinal cross-sectional study all patients who underwent pk or dalk for keratoconus at 2 years period were included to the study. the patients were recalled and complete eye examination including best s...

purpose: to determine the long-term visual outcomes and complications of penetrating keratoplasty (pk) performed for keratoconus. methods: hospital records of patients with keratoconus who underwent pk at the ophthalmology center of shaheed sadoughi, yazd, iran, during 1992-2003 were reviewed. we studied records of 84 pk procedures in 72 keratoconus patients. data including best corrected visua...

Complex pharmacokinetic (PK) properties including nonlinear elimination were encountered by some monoclonal antibodies (mAbs), and classic compartment models sometimes failed to appropriately describe those properties. In this work, a new model was built on a comprehensive analysis of the complex elimination of mAbs. This new model was firstly utilized to fit with the single-dose plasma concent...

Complex pharmacokinetic (PK) properties including nonlinear elimination were encountered by some monoclonal antibodies (mAbs), and classic compartment models sometimes failed to appropriately describe those properties. In this work, a new model was built on a comprehensive analysis of the complex elimination of mAbs. This new model was firstly utilized to fit with the single-dose plasma concent...

background: the frequency of pyruvate kinase (pk) deficiency, an autosomal recessive defect, is approximately 3 per 10,000 individuals in shiraz and surrounding areas, and is increased due to high consanguinity marriage frequency. the purpose of this study is to obtain data on the frequency and spectrum of gene mutation of pk in newborns, from shiraz and surrounding areas. materials and methods...

Background: The frequency of pyruvate kinase (PK) deficiency, an autosomal recessive defect, is approximately 3 per 10,000 individuals in Shiraz and surrounding areas, and is increased due to high consanguinity marriage frequency. The purpose of this study is to obtain data on the frequency and spectrum of gene mutation of PK in newborns, from Shiraz and surrounding areas. Materials and Methods...