A pancreatic islet cell-specific enhancer sequence (PISCES) shared by the rat insulin-I, glucagon, and somatostatin genes binds the paired domain-containing transcription factor Pax6 and confers strong transcriptional activity in pancreatic islet cell lines. It was found recently that Pax6 plays a major role in islet development. In the present study, transgenic mice were used to investigate PI...

PISCES is a database server for producing lists of sequences from the Protein Data Bank (PDB) using a number of entry- and chain-specific criteria and mutual sequence identity. Our goal in culling the PDB is to provide the longest list possible of the highest resolution structures that fulfill the sequence identity and structural quality cut-offs. The new PISCES server uses a combination of PSI...

PISCES is a public server for culling sets of protein sequences from the Protein Data Bank (PDB) by sequence identity and structural quality criteria. PISCES can provide lists culled from the entire PDB or from lists of PDB entries or chains provided by the user. The sequence identities are obtained from PSI-BLAST alignments with position-specific substitution matrices derived from the non-redu...

This paper describes PISCES 1.2E, a system for incremental learning of probabilistic rules. PISCES is efficiently incremental in the sense that both its processing time per instance and its memory usage are independent of the number of training instances. Classification accuracy alone does not provide a sufficient measure of performance for probabilistic classifiers. Additional measures include...

Shared storage services enjoy wide adoption in commercial clouds. But most systems today provide weak performance isolation and fairness between tenants, if at all. Misbehaving or high-demand tenants can overload the shared service and disrupt other well-behaved tenants, leading to unpredictable performance and violating SLAs. This paper presents Pisces, a system for achieving datacenter-wide p...

Nowadays, many MapReduce applications consist of groups of jobs with dependencies among each other, such as iterative machine learning applications and large database queries. Unfortunately, the MapReduce framework is not optimized for these multi-job applications. It does not explore the execution overlapping opportunities among jobs and can only schedule jobs independently. These issues signi...

MILLER, R. R., AND C. L. HUBBS. 1969. Systematics of Gasterosteus aculeatus, with particular reference to intergradation and introgression along the Pacific coast of North America: a commentary on a recent contribution. Copeia 1969:52-69. MOODIE, G. E. E., AND T. E. REIMCHEN. 1976. Phenetic variation and habitat differences in Gasterosteus populations of the Queen Charlotte Islands. Syst. Zool....

It has been demonstrated that the electron density, ne, and temperature, Te, are successfully evaluated from He I line intensity ratios coupled with machine learning (ML). In this paper, ML-aided ratio technique is applied to deuterium (D) plasmas 0.031 < ne (1018 m−3) 0.67 2.3 Te (eV) 5.1 in PISCES-A linear plasma device. Two ratios, Dα/Dγ Dα/Dβ, used develop a predictive model for sepa...

In 2005, medical educators at the University of California, San Francisco (UCSF), began developing the Parnassus Integrated Student Clinical Experiences (PISCES) program, a year-long longitudinal integrated clerkship at its academic medical center. The principles guiding this new clerkship were continuity with faculty preceptors, patients, and peers; a developmentally progressive curriculum wit...

Meiotic maturation is a complex process that involves resumption of meiosis in response to preovulatory luteinizing hormone (LH) surge just before ovulation. High levels of cAMP in oocytes maintain meiotic arrest at diplotene of prophase I in mammals and pisces. In mammals, the process by which LH induces recommencement of meiosis involves breakdown of oocyte-somatic cells communication, which ...