2-Arylpropionic acid derivatives, such as ibuprofen, constitute an important group of non-steroidal anti-inflammatory drugs (NSAIDs). Biocatalytic asymmetric reduction 2-arylacrylic derivatives by ene reductases (EREDs) is a valuable approach for synthesis these derivatives. However, previous bioreduction EREDs resulted solely in nonpharmacological (R)-enantiomers. Here, we present the engineer...

*Correspondence: Fabien Knoll, Departamento de Paleobiología, Museo Nacional de Ciencias Naturales, Consejo Superior de Investigaciones Científicas, C/ José Gutiérrez Abascal 2, 28006 Madrid, Spain e-mail: [email protected] The “stipites” are Bathonian (Middle Jurassic) coals that formed in an everglades-like environment and are now exposed in the Grands Causses (southern France). The vertebra...

Introduction. Cellulose-containing parts of herbs are an excellent source alternative energy and can be used to produce biological ethanol. The present research aims at improving this fundamental promising area biotechnology. It introduces a new consortium microorganisms that saccharify while fermenting the substrate.
 Study objects methods. featured technical cellulose obtained from Misca...

Microorganisms exploit extracellular electron transfer (EET) in growth and information exchange with external environments or with other cells. Every microbial cell is surrounded by extracellular polymeric substances (EPS). Understanding the roles of three-dimensional (3D) EPS in EET is essential in microbiology and microbial exploitation for mineral bio-respiration, pollutant conversion, and b...

background: trypsin modulating oostatic factor (tmof) terminates trypsin biosynthesis in adult and larval mos­quito gut. it will inhibit the growth and development of mosquito larvae feeding on it resulting in death by starvation. the objective of this study is to determine the effective dose of pichia-tmof and the combination of pichia-tmof with bacillus thuringiensi s ( bt) as larvicide on ae...

As a clean and renewable source of energy, ethanol is a promising alternative to fossil fuels.1 Especially lignocelluloses, as raw material for ethanol production, have gained great interest during these years.2 Production of bio-ethanol will help to cope with the over-consumption of fossil fuels and further work for the reduction of carbon dioxide emissions. Lignocelluloses (crop residue, cell...

BACKGROUND Trypsin Modulating Oostatic Factor (TMOF) terminates trypsin biosynthesis in adult and larval mosquito gut. It will inhibit the growth and development of mosquito larvae feeding on it resulting in death by starvation. The objective of this study is to determine the effective dose of Pichia-TMOF and the combination of Pichia-TMOF with Bacillus thuringiensis (Bt) as larvicide on Ae. ae...

Four new yeasts are described that were recognized as novel from nucleotide substitutions in domain D1/D2 of 26S rDNA, a region that is sufficiently divergent to allow resolution of most ascomycetous yeast species. The new species and their type strains are as follows: Pichia maclurae NRRL Y-5377T (= CBS 8671T); Pichia misumaiensis NRRL Y-17389T (= CBS 8062T); Candida mycetangii NRRL Y-6843T (=...