collagen is the major protein component of cartilage, bone, skin and connective tissue and constitutes the major part of the extracellular matrix. collagen type i has complex structural hierarchy, which consists of treepolypeptide α-chains wound together in a rod-like helical structure. collagen is an important biomaterial, finding many applications in the field of tissue engineering. it has be...

This study focuses on determining the effect of varying the composition and crosslinking of collagen-based films on their physical properties and interaction with myoblasts. Films composed of collagen or gelatin and crosslinked with a carbodiimide were assessed for their surface roughness and stiffness. These samples are significant because they allow variation of physical properties as well as...

Gellan Gum (GG) has been recently proposed for tissue engineering applications. GG hydrogels are produced by physical crosslinking methods induced by temperature variation or by the presence of divalent cations. However, physical crosslinking methods may yield hydrogels that become weaker in physiological conditions due to the exchange of divalent cations by monovalent ones. Hence, this work pr...

UV laser crosslinking is a potentially powerful tool to investigate transient DNA-protein interactions and binding kinetics in intact cells. As the processes underlying UV laser crosslinking are not fully understood, we have performed a study of the influence of laser pulses with different physical parameters on crosslinking of the progesterone receptor to an oligonucleotide containing a hormon...

The concept of crosslinking involves a complicated process of formation of chemical bonds between larger molecules that can change the structure of the material, make it stronger and more resistant to decay. Physical crosslinking with ultraviolet light is used in various fields of industry and medicine for increasing the strength of the material. Chemical crosslinking methods are used in stomat...

There is a general interest among paper and board makers to produce lighter and bulkier paper and board products. The aim of the present study was to characterize chemically crosslinked hardwood kraft fibers regarding their potential in making bulky paper and board. Crosslinking agents are molecules that contain two or more reactive ends that form inter-chain covalent bonds with cellulosic hydr...

Elastomers or rubbers are materials used in a large range of industrial and household applications. A common physical-chemical treatment is curing (crosslinking), imparting the rubber mechanical and thermal stability. Elastomers show low thermal conductivity values, and therefore, require complex and high cost heating methods; thus, the ionizing (accelerated electrons) method shows high interes...