Introduction: The perennial herb Phyllanthus niruri, belonging to the family Euphorbiaceae is commonly known as Bhuiavala in Marathi and possess antibacterial, analgesic, antipyretic, anti-hepatotoxic, antifungal and anthelmintic activity. Objective: The present study was carried out to validate the in vitro anthelmintic activity of hot aqueous whole plant extract of Phyllanthus niruri against ...

HIV is the etiological agent of AIDS that has created major health care problem throughout the world. The aim of the present study is to evaluate the cytotoxic effects and anti-HIV activity of Phyllanthus niruri whole plant extracts. Hexane, chloroform, ethyl acetate, acetone and methanol solvents were used to prepare the extracts by sequential maceration method. RetroSys HIV-1 RT (Innovagen, S...

clude some 500 species and are widespread in temperate and tropical climates. Phyllanthus species have attracted the attention of researchers for their hepatoprotective properties; an aqueous extract of Phyllanthus amarus was demonstrated to exert antihepatitis B virus effects to varying degrees. In 2003, various constituents isolated from Phyllanthus species were screened for anti-human hepati...

In spite of considerable efforts to identify effective treatments for urolithiasis, this is a goal yet to be achieved. This review summarizes experimental and clinical data evaluating the effect of the plant Phyllanthus niruri, a plant with worldwide distribution, as a potential agent to prevent and/or to treat urolithiasis The review is based on data from the literature and on the results obta...

Phyllanthus niruri L. (Euphorbiaceae) is a well-known hepatoprotective herbal plant. The aim of this study was to investigate the hepatoprotective action of the protein isolate of Phyllanthus niruri (P. niruri) against acetaminophen (APAP) induced hepatotoxicity. Protein isolate of P. niruri was intraperitoneally injected in mice either prior to (preventive) or after the induction of toxicity (...

The present work was designed to evaluate the antimicrobial activities of the ethanol extract of different parts of Phyllanthus niruri (EPN) (Family: Euphorbiaceae). The antimicrobial activity of EPN was determined by the well diffusion method with various gram-positive, gram-negative microorganisms and pathogenic fungus. We have collected medicinally important medicinal plant Phyllanthus nirur...

Phyllanthus niruri extract is extensively used in treating liver ailments. Effects of aqueous extract of P. niruri on liver, kidney and testes of CCl4 induced hepatotoxic rats were studied. High levels of malondialdehyde (MDA) were observed in the CCl4 test group with significant reduction of MDA levels in all groups on P. niruri extract administration. Highest levels of glutathione (GSH) were ...

The present article describes the chemical characteristics such as pH of aqueous extract, fluorescence, aqueous and alcoholic extractives, lignans and TLC profile of aqueous extract of Bhuiavli (Phyllanthus niruri).

In the present study the effect of alcholic extract of the Phyllanthus niruri whole plant on rat biochemical and serum marker enzymes against Staphylococcus aureus induced oxidative stress in the rat liver. Pre and post-treatment with extract showed a dose-dependent reduction of Staphylococcus aureus induced rats were elevated levels of enzyme activity with parallel increase in total protein an...

BACKGROUND The medicinal plants signify a massive basin of potential phytoconstituents that could be valuable as a substitute to allopathic drugs or considered as an analogue in drug development. Phyllanthus niruri L. (Euphorbiaceae) is generally used in traditional medicine to treat ulcer and inflammation. In this project we investigated the methanolic extract of leaves of Phyllanthus niruri f...