In a study of human yawning Robert Provine (1986) remarked that yawning is a prominent stereotyped action pattem and releasing stimulus which “does not deserve its current status as a minor behavioural curiosity”. Indeed, “yawning may have the dubious distinction of being the least understood, common, human behaviour”. In contrast, a large body of experimental data has been collected during the...

rosa damascena mill l., known as gole mohammadi in iran is one of the most important species of rosaceae family flowers. r. damascena is an ornamental plant and beside perfuming effect, several pharmacological properties including anti-hiv, antibacterial, antioxidant, antitussive, hypnotic, antidiabetic, and relaxant effect on tracheal chains have been reported for this plant. this article is a...

background: the nigella sativa l. seeds have been used as herbal medicine in several countries for the treatment and prevention of a wide range of diseases like cough and bronchial asthma, headache, nasal congestion, toothaches, intestinal worm, menstrual disorder, digestive abnormality, and impotence. objective: the aim of this review was to collect updated available data focused on the pharma...

Headaches are common in children and adolescents, and are the most common pain complaint when seeking medical advice. Primary headaches are one of the most common disorders of childhood, with migraine and tension type headache being the most prominent. Treatment strategies for primary headaches vary according to patient’s age, family structure, culture and beliefs, headache diagnosis, and accor...

Molecular imaging using PET provides a unique tool for noninvasively investigating the biochemistry of living organs. The wide range of radiolabeled molecules makes it possible to explore various biochemical, physiologic, and pharmacologic processes in vivo. Because each radiotracer is characterized by its particular kinetic behavior in the human body, the quantification of this behavior is a c...

one of the most common health problems are diseases of the cardiovascular system with a great bulk of disease burden; while a considerable number of cardiac patients undergo cardiac surgery; cardiac surgical procedures with cardiopulmonary bypass (cpb) are nowadays among the top list of surgical procedures. more than half of a century has passed since the introduction of total cardiopulmonary b...

objective: today, medicinal plants are widely used in remedies for several ailments and improvement of human health because of their pharmaceutical properties. this study aimed to document important useful medicinal plants and their medicinal characteristics for treatment of human ailments in the arjan _ parishan protected area in fars province of iran during 2010-2012. materials and methods: d...

Dysfunction of β -glucocerebrosidase (GCase) has no hydrolytic activity in patients of Gaucher's disease and increasing the risk factor for Parkinson's disease occurrence. Pharmacological chaperone design has been used to treat with misfolded protein in related disease, which utilized a small compound to cause protein folding correctly. This study employed the world largest traditional Chinese ...

INTRODUCTION Mutations in the gene encoding for acid β-glucosidase (β-glucocerebrosidase, GlcCerase) are seen in Gaucher disease (GD), which give rise to significant protein misfolding effects and result in progressive accumulation of glucosyl ceramide. The main treatment for GD is enzyme replacement therapy (ERT). The iminosugar glycosidase inhibitor N-(n-butyl)-1-deoxynojirimycin (miglustat, ...