in this study, a simple and reliable square wave voltammetric (swv) method was developed and validated for determination of diclofenac in pharmaceutical preparations and human serum. the proposed method was based on electrooxidation of diclofenac at platinum electrode in 0.1 m tbaclo4/acetonitrile solution. the well-defined two oxidation peaks were observed at 0.87 and 1.27 v, respectively. cal...

2 Feb 00 Levaquin (injectable, tablet) Levofloxacin R. W. Johnson Pharmaceutical Research Institute, Ortho Pharmaceutical Corp. For treatment of levofloxacin-susceptible, penicillin-resistant S. pneumoniae in patients with community-acquired pneumonia 3 Mar 00 Biaxin XL Filmtab (extended-release tablet) Clarithromycin Abbott Laboratories For acute exacerbations of chronic bronchitis and acute m...

In the last decade, interest in developing a combination of two or more Active Pharmaceutical Ingredients (API) in a single dosage form (monolithic or bilayer tablet) has increased in the pharmaceutical industry, promoting patient convenience and compliance. Bilayer tablets can be a primary option to avoid chemical incompatibilities between API by physical separation, and to enable the developm...

The analysis of the distribution of pharmaceutical materials in tablet formulations, such as drugs and matrix elements, is critical to product performance and is used in such areas as quality control, impurity testing, and process monitoring. Recently imaging techniques, such as Raman, near-IR, and fluorescence imaging, have become popular for “visualization” of pharmaceutical formulations, all...

In the pharmaceutical science, sintering has been described as the mechanism for the strengthening of the mechanical properties of consolidated pharmaceutical powders at elevated temperatures, for solid-bond formation during tablet compression, and for thermal curing of polymer-latex film coatings. The concept of sintering was applied in the investigation of the effect of heating on the mechani...

The kinetic (or sliding) friction of pharmaceutical tablets and capsules influences how they will behave during the conveying, coating, and packaging operations that are used for drug product manufacturing. In order to logically design equipment for manufacturing and packaging operations, and to simulate manufacturing and packaging performance (for example, using discrete or finite element mode...

Bi-layer tablet is a new era for the successful development of controlled release formulation along with various features to provide a way of successful drug delivery system. Bi-layer tablet is suitable for sequential release of two drugs in combination, separate two incompatible substances and also for sustained release tablet in which one layer is immediate release as initial dose and second ...

Each active light yellow tablet contains: Ethinylestradiol 30 micrograms Drospirenone 3 mg For full list of excipients, see section 6.1 List of excipients. 3. PHARMACEUTICAL FORM YASMIN active tablet Light yellow round film-coated tablets marked on one side with the letters “DO” in a regular hexagon, each containing drospirenone 3 mg and ethinylestradiol 30 μg. YASMIN placebo tablet White, roun...