a simple, sensitive and accurate method for spectrophotometric determination of dalacinphosphatehas been established. the method is based on the reduction of atomic absorptioncalcium ion by phosphate. because, there is a phosphate mole in every dalacin mole structureand with measurement of phosphate, dalacin is beyond measurement too. therefore, the reactionbetween acidic hydrolysis products of...

a novel potentiometric ion-selective pvc membrane sensor for analysis of atorvastatin (at) in pharmaceutical preparations based on atorvastatin-(tetraphenyl borate), (at-(tpb)2) as sensing element, tetraphenyl borate as additive and tris-2-ethyl-hexyl phosphate (top) as plasticizer solvent was prepared. the electrode shows a good nernestian response over the concentration range of 0.09–5586 µg ...

Ryozo oishi, Ph.D., is Professor and Director, Department of Pharmacy, Kyushu University Hospital, Higashi-ku Maidashi 3-1-1, Fukuoka, Japan ([email protected]). Susan R. Dombrowski, M.S., is acknowledged for her assistance with this article. Dr. Oishi received an honorarium from the International Pharmaceutical Federation for preparing this article and acting as a working-group f...

Biological and pharmaceutical samples represent formidable challenges in sample preparation that hold important consequences for bioanalysis and genotoxic impurity quantification. This Feature will emphasize significant advances toward the development of rapid, sensitive, and selective sample preparation methods.

Supercritical fluid technologies (SCFT) represent a recent approach for obtaining pharmaceutical materials in pure physical form and the application of supercritical fluids is a superior alternative to conventional precipitation and extraction processes. Supercritical fluid technology (SCFT) offers exciting opportunities to produce and modify pharmaceutical substances and has the potential to r...