a radio assay employing 14c-uridine to measure the intracellular killing of candida albicans by phagocytes is presented. the principle of this new method is that after killing of candida albicans by phagocytes rna synthesis stops and therefore uridine uptake is diminished whilst viable candida in cultures would take up uridine and as a result, high cpm counts can be obtained within 135 min. of ...

A radio assay employing 14C-uridine to measure the intracellular killing of Candida albicans by phagocytes is presented. The principle of this new method is that after killing of Candida albicans by phagocytes RNA synthesis stops and therefore uridine uptake is diminished whilst viable candida in cultures would take up uridine and as a result, high CPM counts can be obtained within 135 min...

background: there are reports about the increase of severity of infections in patients receiving morphine. therefore this study was aimed to evaluate the effect of morphine on phagocytic activity of peritoneal phagocytes of mice. methods: fifty six female balb/c mice, 6-8 weeks old and 28±2 gram weight, were divided into two groups. the case group received 20, 40, 60 and 80 mg/kg morphine on fi...

Chronic liver disease is a complex multi-stage process involving many immune and non-immune cells. Understanding the pathology of diseases requires knowledge cell biology phagocytes. The review summarizes our current perception role phagocyte cells innate system in chronic inflammation, with an emphasis on their interaction inflammatory participants. A better understanding response may serve as...

In article number 2100370, Alexandros Marios Sofias, Sjoerd Hak, and co-workers, report that cRGD-decorated lipid nanoparticles target inflammatory lesions via hitchhiking with phagocytes. Through a complementary approach including state-of-the-art intravital microscopy, it is identified neutrophils monocytes take up liposomes nanoemulsions in circulation subsequently home to the lesion. Cover ...

Leukocytes isolated from patients with polycythemia vera (PCV), a panmyelopathy, have increased metabolic activity during the resting and phagocytizing states. Phagocytes from patients with PCV were studied by counting particle ingestion, measuring hexose monophosphate shunt (HMP) activity by the conversion of glucose1-’4C tr, ‘4CO2, and determining 02 consumption and nitroblue tetrazolium (NBT...

Deficiences imunitaire acquises Les , deficits nnmumtaires pathologiques af­ systeme des phagocytes, l'immunite a mechation_ cellulare :t la synthese des im­ Illfnoglobulmes so1t separement, soit con­Jom temen t. La manifestation .clinique de ces deficits est la ,frequence _des mfections bacterielles, vir­ales et mycotiques.  Le triteJent s deficits immunitaire a part la therap1e antnnfectieu...