oral ph sensitive drug delivery systems are of utmost importance as these systems deliver the drug at specific part of the gastrointestine (gi) as per the ph of gi, resulting in improved patient therapeutic efficacy and compliance. the ph range of fluids in various segments of the gi tract may provide environmental stimuli for drug release. the aim of this study was to design buoyant beads cont...

the aim of the research work was to chemically modify guar gum(gg) as a ph sensitive co-polymer and formulating intestinal targeting eso nanoparticles (nps) using the synthesized co-polymer. poly acrylamide-grafted-guar gum (paam-g-gg) co-polymer was synthesized by free radical polymerization. chemical modification of paam-g-gg by alkaline hydrolysis results in formation of a ph-sensitive co-po...

to answer challenge of targeted and controlled drug release in oral delivery various materials were studied by different methods. in the present paper, controlled metal based drug (pd(ii) complex) release manner of β‑lactoglobulin (β-lg) nanoparticles was investigated using mathematical drug release model in order to design and production of a new oral drug delivery system for gastrointestinal ...

drug-in-adhesive transdermal drug delivery systems  )tddss) containing stimulants, termed as energetic substances, such as caffeine and pantothenic acid, were studied. caffeine is a white crystalline substance and a stimulant to central nervous system. in humans, caffeine acts as a central nervous system stimulant, temporarily warding off drowsiness and restoring alertness. pantothenic acid, al...

The oral route is the preferred route for drug delivery, among oral delivery Intestine and colon drug delivery have been used for molecules aimed at local treatment of colonic diseases such as Colon Cancer, Polyp, Colorectal, Crohn’s Disease, Inflammatory Bowel Disease (IBD), Ulcerative Colitis (UC) etc. and for delivery of molecules susceptible to enzymatic degradation such as peptides. There ...