Background and aims Personalized feedback interventions (PFI) have shown success as a low-cost, scalable intervention for reducing problematic and excessive consumption of alcohol. Recently, researchers have begun to apply PFI as an intervention method for problematic gambling behaviors. A systematic review of the literature on PFI as an intervention/prevention method for gambling behaviors was...

Background The Peripheral Perfusion Index (PFI) has been utilized for early detection of impaired organ perfusion in order to avoid tissue hypoxia, which could lead to organ failure [1]. A decrease in effective circulating blood volume, lowering of PFI levels, can cause vasoconstriction [2]. Strong MRI magnetic field (B0) interactions with flowing blood plasma electrolytes produce a Magnetohydr...

Using the simplex method (SM) is one of the most effective ways of solving large scale real life linear optimization problems. The efficiency of the solver is crucial. The SM is an iterative procedure, where each iteration is defined by a basis of the constraint set. In order to speed up iterations, proper basis handling procedures must be applied. Two methodologies exist in the state-of-the-ar...

SETD7 is associated with multiple diseases related signaling pathways. (R)-PFI-2 is the first SETD7 inhibitor with nanomolar inhibitory potency. The activity of (R)-PFI-2 is about 500 times over that of (S)-PFI-2. Understanding the mechanism behind this difference will be helpful to discovery and design of more potent SETD7 inhibitors. A computational study combining molecular dynamics simulati...

The concept of value for money (VFM) is the fundamental reason for most PFI projects to be attractive in many developed and developing countries. The concept encourages governments to deliver Mega projects by using PFI procurement method. The aims of this paper are to investigate the notion of VFM for PFI projects by different countries (i.e. UK, Australia and Japan) and to discover the detaile...

Published by Reporters Without Borders every year, the Press Freedom Index (PFI) reflects the fear and tension in the newsroom pushed by the government and private sectors. While the PFI is invaluable in monitoring media environments worldwide, the current survey-based method has inherent limitations to updates in terms of cost and time. In this work, we introduce an alternative way to measure ...

In the United Kingdom (UK), Public Private Partnerships (PPP), in the guise of the Private Finance Initiative (PFI), has become an integral part of national government policy in the delivery of public facilities and services. The aim of introducing the PFI was to achieve closer partnering between the public and private sectors at both central government and local authority levels. Despite the P...

Discovering Probabilistic Frequent Itemsets (PFI) in uncertain data is very challenging since algorithms designed for deterministic data are not applicable in this context. The problem is even more difficult for uncertain data streams where massive frequent updates need be taken into account while respecting data stream constraints. In this paper, we propose FMU (Fast Mining of Uncertain data s...

Discovering Probabilistic Frequent Itemsets (PFI) is very challenging since algorithms designed for deterministic data are not applicable in probabilistic data. The problem is even more difficult for probabilistic data streams where massive frequent updates need to be taken into account while respecting data stream constraints. In this paper, we propose FEMP (Fast and Exact Mining of Probabilis...

Much of the literature on value for money (VFM) evaluation of private finance initiative (PFI) contracts has concentrated on the financial methodology of constructing the public sector comparator (PSC) and its limitations. In contrast, this paper focuses on examining how ‘PFI bids’ are actually evaluated for VFM in the case of three secondary school PFI contracts. It is a unique study which pre...