background: in radiation therapy, the peripheral dose is important when anatomical structures with very low dose tolerances are involved. in this study, the two available calculation algorithms of the varian eclipse 8.6 treatment planning system(tps), the anisotropic analytic algorithm (aaa) and pencil-beam convolution (pbc) was used to compare measured and calculated peripheral dose distributi...

Background: In radiation therapy, the peripheral dose is important when anatomical structures with very low dose tolerances are involved. In this study, the two available calculation algorithms of the Varian Eclipse 8.6 treatment planning system(TPS), the anisotropic analytic algorithm (AAA) and pencil-beam convolution (PBC) was used to compare measured and calculated peripheral dose distributi...

background: because of the adverse effects of ionizing radiation on fetuses, prior to radiotherapy of pregnant patients, fetal dose should be estimated. fetal dose has been studied by several authors in different depths in phantoms with various abdomen thicknesses (at). in this study, the effect of maternal at and depth in fetal dosimetry was investigated, using peripheral dose (pd) distributio...

background: in radiation therapy, peripheral dose or the dose outside the radiotherapy field, is important when anatomical structures with very low dose tolerances are involved. one of these critical organs in pelvic irradiation is testis. the amount of radiation delivered to the testes in radiotherapy must be kept as small as possible, consistent with the limit dose of this organ. the threshol...

background: the purpose of this paper is to establish an easy and reliable biodosimeter protocol to evaluate the biological effects of proton beams. materials and methods: human peripheral blood lymphocytes were irradiated using proton beams (let: 34.6 kev μm−1), and the chromosome aberrations induced were analyzed using cytokinesis-blocked (cb) micronucleus (mn) assay. to determine the efficie...

Introduction: The use of electrons in the electron therapy to destroy tumoral tissue is dedicated significant contribution of different methods of radiation therapy. Scattered radiation due to exited electrons of the applicator affect the dose out of the field in the patient's normal tissue. The aim of this study is to determine the peripheral dose outside the applicator in the...

background: 3dcrt (three-dimensional conformal radiotherapy) and imrt (intensity-modulated radiotherapy) has provided us with tools to delineate the radiation dose distribution of tumor targets. however, the precision of radiation can be compromised by respiratory motion, which usually limits the geometric and dosimetric accuracy of radiotherapy. the purpose of this study is to evaluate the imp...

paclitaxel is a highly effective anticancer agent. it is active against a broad range of cancers that are generally considered refractory to conventional chemotherapy. paclitaxel induces a peripheral neuropathy (pn) that is characterized by sensory symptoms such as numbness and paresthesia in a glove and stocking distribution. pn may be severe and dose limiting at initial doses above 275 mg/m2....