Following extraperiosteal injections of saline, serum, or whole blood, the synthesis of DNA in the cells of the osteogenic layer of the femora of mice was stimulated to approximately two-thirds of the level obtained by fracture of the femora. Irrespective of the material injected, the proliferative response of the cells in the periosteum was similar. These studies have shown that neither bone f...

The goal of our research work is to establish mesenchymal osteoprogenitors derived from human jaw periosteum for tissue engineering applications in oral and maxillofacial surgery. For future autologous and/or allogeneic transplantations, some issues must be addressed. On the one hand, animal-free culture conditions have yet to be established. On the other hand, attempts should be undertaken to ...

Oral surgical procedures occasionally require removal of the periosteum due to lesions, and these raw bone surfaces are prone not only to infection but also to scar formation during secondary healing. The objective of this study was to identify successful methods for reconstruction using periosteal defect dressings. We created 1-cm2 defects in the skin and cranial periosteum of 10-week-old male...

The cambium cells of the periosteum, which are known osteoprogenitor cells, have limited suitability for clinical applications of tissue engineering in their native state due to their low cell number (2-5 cells thick). Extracorporeal shock waves (ESWs) have been shown to cause rapid periosteal cambium cell proliferation and subsequent periosteal osteogenesis. This work investigates a novel stra...

Background: Aortic thrombosis (ATh) is an uncommon problem in dogs. Although the pathogenesis of hypertrophic osteopathy (HO) is unknown, it is thought this can be due to blood flow disorder. In this case, removal of aortic thromboembolism (ATE) resulted in periosteal proliferation. Case description: A 4.8-kg, 3-year-old, intact female Maltese was referred with...

Gingival overgrowth commonly seen in clinics can be categorized as generalized or localized. Peripheral giant cell granuloma (PGCG) is tumor like, non-neoplastic reactive intra-osseous lesion occurring the gingiva alveolar mucosa and characterized by an un-encapsulated proliferation of mononuclear polygonal cells which are spindle-shaped with osteoclast-type multinucleated a vascular background...

The periosteum is a thin membrane that surrounds the outer surface of bones and participates in fracture healing. However, the molecular signals that trigger/initiate the periosteal reaction are not well established. We fractured the rat femoral bone at the diaphysis and fixed it with an intramedullary inserted wire, and the expression of regenerating gene (Reg) I, which encodes a tissue regene...

BACKGROUND The use of the Masquelet technique in the repair of large bone defects has gained increased acceptance in recent years. The core of this technique is the induction of granulation tissue membrane formation and the implantation of an autologous cancellous bone to reconstruct bone defects in the membrane. In this study, we purpose to explore the structure of induced membrane and the con...