conclusions with a thorough preoperative assessment incorporating focused echocardiography, anaesthetists are in the unique position to enhance their role as perioperative physicians and influence short and long term outcomes of their patients. context patients with undifferentiated systolic murmurs present commonly during the perioperative period. traditional bedside assessment and auscultatio...

background: we observed the clinical effects of comprehensive nursing intervention pattern in 23g minimally invasive vitreous surgery according to the comprehensive nursing intervention table developed by our hospital, which would supply a basis for its clinical application. methods: in this prospective study, we followed 120 patients undergoing 23g minimally invasive vitreous surgery from xuzh...

background: statins (3-hydroxy-3-methylglutarylcoenzyme-a (hmg-coa) reductase inhibitors) decrease cardiovascular mortality and morbidity. this article reviews the role of perioperative statins in non cardiac surgery. methods: a literature review was done on all english published articles till february 2015 about this subject using pubmed. then the reference list of relevant articles was review...

Therefore this chapter will first focus on aspects of acid-base physiology that are relevant to most anesthesiologists. It will become clear that acid-base disorders may have a major clinical impact both on the patient scheduled for anesthesia and anesthetic drugs. But even more importantly, many clinical interventions by anesthesiologists may actually profoundly influence [H+] itself. The impo...

Potassium ions play a vital role at a cellular level. These ions are actively transported into cells, causing an electrical imbalance and a build up of potential energy. When this energy is released following correct stimulation, the cells perform their designated functions. When these functions relate mainly to the heart and skeletal muscles, nerve and renal activity, the importance of potassi...

The perioperative period is characterized by profound changes in the body's homoeostatic processes. This review seeks to address whether epigenetic mechanisms may influence an individual's reaction to surgery and anaesthesia. Evidence from animal and human studies suggests that epigenetic mechanisms can explain many facets of susceptibility to acute and chronic pain, making them potential thera...

Anesthesiologists use a myriad of drugs during the provision of an anesthetic. Many of these drugs have side effects that are dose related, and some lead to severe immune-mediated adverse reactions. Anaphylaxis is the most severe immune-mediated reaction; it generally occurs on reexposure to a specific antigen and requires the release of proinflammatory mediators. Anaphylactoid reactions occur ...