background & objective:  periodic paralyses are a group of rare disorders that cause temporary episodes of muscle weakness or paralysis.  hypokalemic periodic paralysis usually is transmitted by an autosomal dominant trait with more penetration in men.  hypokalemic periodic paralysis may be secondary to thyrotoxicosis, hyperparathyroidism, drug  toxicity and potassium losing states. sporadic fo...

primary hypokalemic periodic paralysis is a familial channelopathy inherited as an autosomal dominant trait. the first attack of paralysis may be evolved at any age, but has been reported to be most common in the second decade, so that some authorities believe that an episodic weakness beginning after age 25 is almost never due to primary periodic paralysis. in this retrospective study, we revi...

0

the myotonic disorders are a heterogeneous group of genetically determined diseases that are unified by the presence of myotonia, which is defined as failure of muscle relaxation after activation. the presentation of these disorders can range from asymptomatic electrical myotonia, as seen in some forms of myotonia congenita (mc), to severe disability with muscle weakness, cardiac conduction def...

Thyrotoxic periodic paralysis is a unique disorder that causes episodic proximal lower extremity muscle weakness in patient who already has hyperthyroid state and not treated for the underlying disease state. The affected population mostly includes Asian origin specifically male gender (vs most thyroid affects women gender). Precipitating factors include addition to are strenuous exertion, high...

background: normokalemic periodic paralysis is an autosomal dominant disorder involving the abnormal function of skeletal muscle’s voltage-gated alpha-subunits. it is characterized by paralysis attack of varying severity with concomitant normal serum potassium concentration. although normokalemic periodic paralysis is well established in the literature, but its cardiac manifestations are very r...

Thyrotoxic periodic paralysis (TPP) attacks are characterized as recurrent, transient episodes of muscle weakness that range from mild weakness to complete flaccid paralysis. Episodes of weakness are accompanied by hypokalemia, which left untreated can lead to life-threatening arrhythmias (6). In this case study, we followed a patient's potassium levels analyzing how they correlate with electro...

Thyrotoxic Periodic Paralysis (TPP) is a rare and life threatening condition commonly occurring in young Asian males. It is characterized by acute paralytic attacks and hypokalemia in association with thyrotoxicosis. Serum potassium levels may be normal in rare cases of TPP. The diagnosis of normokalemic TPP may be overlooked and/or delayed in most cases. Here, we describe a 32-year-old Iranian...

た.し か し発熱,筋 ・関節痛はな く,知 覚異常も 自覚 しなかつた.筋 脱力は四肢に限局し,頭 頚部 およ び躯幹の異常はなかつた.発 病後約1週 間徐 徐に増悪 したのち快方に向い,約1ヵ 月間の通院 治療で全治した.そ の後は特別の症状なく普通に 生活 していたがが,昭 和43年(15才 時)8月 初旬, 野球大会に投手 として出場のための練習で過労がが 続いたのち,同 月12日,最 終試合を 終えて 帰宅 後,夕 食前,午 後6時 頃から両手の脱力を覚え, 翌13日 朝は両下肢 の脱力が加わ り,さ らに夕刻に は軽度の嚥下障害も認められ,14日 には腰腹筋脱 力,15日 には起坐 ・歩行全 く不能 とな り,8月17 日当科に入院 した. 入院時現症:意 識清明.起 坐 ・歩行全 く不能 で受動的背臥位であるが,心 ・肺お よび腹部内臓 には異常なく,軽 度の嚥下障害を...

Recent research interest in Karoo tick paralysis and its vector. Ixodes rubicundus, prompted this survey to determine the economic implications of this disease. The survey indicated relatively high losses caused by the condition, identified the stock involved and provided data on the incidence of paralysis and on the control methods employed. Recommendations are made to institute chemical contr...