one of the signifiant risk factor of ischemic stroke is carotid artery occlusion. although surgical treatment was disappointing in these patient but there is a growing reports of sucessful endovascular treatment recently. in this technical note 56 year-old man who suffered from bilateral carotid occlusion was revascularized. the penumbra thrombosuction system was applied to reduce the risk of d...

Background: Due to the small size of the beamlets in IMRT (intensity modulated radiotherapy), physical penumbra is one of the important dosimetric parameters and small changes in the penumbra have a notable impact on the results. The physical penumbra width is defined as the lateral distance between two specified isodose curves at a specified depth of phantom. In this study, after demonstrating...

Introduction: Because of small size of the beamlets in IMRT, physical penumbra is one of the important dosimetric parameters and small changes in the penumbra will have a great impact on the results. The physical penumbra width is defined as the lateral distance between two specified isodose curves at a specified depth of phantom. In this study, after demonstrating the inconsi...

Mortality associated with the occlusion of large vessels in acute ischemic stroke is particularly high despite best available medical therapy. Early and safe revascularization of the primary occlusion is correlated with good clinical result. We report two patients with acute ischemic stroke in whom the mechanical device Penumbra System was used for thrombolysis and embolectomy. The Penumbra Sys...

Stroke, the loss of neurons after ischemic insult to the brain, is one of the leading causes of death and disability worldwide. Despite its prevalence and severity, current therapy is extremely limited, highlighting the importance of further understanding the molecular events underlying ischemia-induced neuronal cell death. An ischemic area can be subdivided into two separate pathophysiological...

BACKGROUND Higher reperfusion rates have been established with endovascular treatment for acute ischemic stroke patients. There are limited data on the comparative performance of mechanical thrombectomy devices. This study aimed to analyse the efficacy and safety of the stent retriever device (Solitaire stent) by comparing procedure time, angiographic outcome, complication rate and long term cl...

The uncombed penumbral model explains the structure of the sunspot penumbra in terms of thick magnetic fibrils embedded in a magnetic surrounding atmosphere. This model has been successfully applied to explain the polarization signals emerging from the sunspot penumbra. Thick penumbral fibrils face some physical problems, however. In this contribution we will offer possible solutions to these s...

Prel iminary results of tbe measurements of the electroQ and ion components of plasma obtained by means of wide-angle detectors onboard the Venera-9 and Venera-l0 satell ites are presented. Stable electron and fluctuating ion fluxes were detected in the optical and corpuscular umbra. As a result of the plasma characteristics ob­ served at a few hundred kilometers above the optical umbra, we ref...

Existing endovascular options for lower extremity and visceral arterial thromboembolism face the challenges of limited trackability, vessel injury, and incomplete revascularization. At the forefront of advances in catheter materials and technology, Penumbra, Inc. recently introduced the IndigoTM System for mechanical thrombectomy in the periphery. The Indigo System is designed to address the li...