OBJECTIVE  A study of the utilization pattern of pre-anesthetic medications in major surgical procedures. MATERIAL AND METHODS  A cross-sectional, pharmacoepidemiological study was conducted among patients undergoing surgical procedures in routine or emergency conditions under general anesthesia. The utilization of pre-anesthetic medicines in all patients was reported. RESULTS A total of 11...

this experimental study was done in order to determine the effect of pentozocin to antagonise respiratory   depression due to fentanyle during general anesthesia in selected hospitals of the medical science university of iran and tehran.   subjects of this study consisted of 50 patients who were chosen randomly, and divided into two group of 25   each. group one received pentazocine before the ...

The aim of the present study was to evaluate the Analgesic & anti inflammatory activities of the Momordica charantia extract. Momordica chirantia (MC) is a herbal medicine traditionally applied to treat so many diseases and disorders. In the evaluation of analgesic activity the model used was Eddy’s hot plate method in which the animals treated with Momordica charantia and standard Pentazocin h...

Purpose: To investigate the anti-inflammatory and analgesic activities of the Amorphophallus Bulbifer in Wistar rats and mice. Methods: The anti-inflammatory activity of the hydroalcohol extract of A. bulbifer whole plant at dose levels of 100 and 200 mg/kg p.o. in rats was determined with a plethysmograph paw volume difference of the animals preand post-treatment. Ibuprofen (10 mg/kg) was empl...

Present study reports analgesic activity of petroleum ether, chloroform, ethyl acetate and methanolic extracts of leaves and seeds of Trigonella foenum-graecum Linn. (Fabaceae) using hot plate method for evaluation of central analgesic activity and acetic acid induced writhing test for evaluation of peripheral analgesic activity in mice.   All the extracts of Trigonella foenum-graecum ...

present study reports analgesic activity of petroleum ether, chloroform, ethyl acetate and methanolic extracts of leaves and seeds of trigonella foenum-graecum linn. (fabaceae) using hot plate method for evaluation of central analgesic activity and acetic acid induced writhing test for evaluation of peripheral analgesic activity in mice.   all the extracts of trigonella foenum-graecum showed si...

Pterospermum acerifolium (L) Willd (Family: Sterculiaceae) has long been used traditionally for the treatment of painful inflammatory conditions in the Indian folk medicine. Objective: In the present study we have evaluated antinociceptive effects and anti-inflammatory effects of unsaponified petroleum ether extract of Pterospermum acerifolium leaves (USPEL, 100 and 200 mg/kg orally) and isolat...

Chandrashekar. R* and S.N. Rao * & Dept of Pharmacology, Yenepoya Medical College, Yenepoya University, Derlakatte, Mangalore 575018. ABSTRACT : The aim of the study was to investigate the chronic peripheral analgesic activity of Ethanolic Extract of the leaves of Clerodendrum viscosum (EECV) by acetic acid induced writhing reflex test in mice and chronic central analgesic activity of EECV by t...

s: Background: Critically ill patients are admitted in Intensive coronary care unit. The intensive coronary care unit (ICCU) is a setting where a large number of drugs are administered to patients. Information on drug utilization in intensive coronary care units (ICUs) are lacking in India. Objectives: To identify pattern of drug use and suggest measures. Methods: Prospective drug utilization s...

A series of 3-substituted-2-thioxoquinazolin-4(3H)-one derivatives have been synthesized and their structures have been elucidated on the basis of IR, (1)H-NMR, elemental analysis and mass spectroscopic studies. Anti-inflammatory and analgesic activity of the synthesized compounds was evaluated by Carrageenan induced rat paw edema method and Eddy's hot plate method respectively. Among the synth...