INTRODUCTION Pemphigoid gestationis, also known as herpes gestationis, is a rare autoimmune blistering disease associated with pregnancy. It usually occurs during the second or third trimester, but it may be present at any stage of pregnancy or the puerperium. The clinical, histologic, and immunopathological features of pemphigoid gestationis are similar to those of the pemphigoid group of diso...

Pemphigoid gestationis (PG), first described in 1872 by Laws Milton, is a rare autoimmune bullous disease of pregnancy and puerperium. Pemphigoid gestationis has been estimated to occur in 1: 50 000 pregnancies and usually presents in the second or third trimester with exacerbation after partum. This disease is caused by circulating IgG1 immunoglobulin against hemidesmosomal protein bullous pem...

Background: Pregnancy-specific dermatoses represent a group of pruritic skin diseases unique to pregnancy and the most common types are polymorphic eruption of pregnancy and pemphigoid gestationis. It is difficult to obtain a histopathological diagnosis for polymorphic eruption of pregnancy and pemphigoid gestationis in the lack of immunofluorescence because of their similar clinical presentati...

1. Castro LA, Lundell RB, Krause PK, Gibson LE. Clinical experience in pemphigoid gestationis: report of 10 cases. J Am Acad Dermatol. 2006;55:823--8. 2. Juárez Fernández R, Medina Montalvo S, Trasobares Marugán L, García Rodríguez M. Herpes gestationis tratado con ciclosporina y corticosteroides. Actas Dermosifiliogr. 2001;92:302--4. 3. Jolles S. A review of high-dose intravenous immunoglobuli...

Pemphigoid gestationis is a rare vesiculobullous dermatosis of pregnancy and puerperium. It is commonly seen in second or third trimester. Skin lesions are characterized by pruritic, urticarial plaques with the development of tense vesicles and bullae. Histopathology demonstrates a subepidermal eosinophil-rich vesiculation. Direct immunofluorescence microscopy reveals linear complement 3 and im...

Pemphigoid gestationis (PG) is a rare vesiculobullous dermatosis of pregnancy. It is commonly seen in second or third trimester. The diagnosis is frequently made with direct immunofluorescence studies of perilesional skin. Prompt recognition and appropriate management may reduce morbidity of this disease. Herein we present a case of pemphigoid gestationis occurring in a 33-year-old primigravida...

Pemphigoid diseases are a group of well defined autoimmune disorders. The most common of these diseases is bullous pemphigoid, which. Abstract Bullous pemphigoid BP is a blistering skin disease. Plex and includes bullous pemphigoid, pemphigoid gestationis, mucous.Bullous pemphigoid BP is an autoimmune subepidermal bullous dermatosis defined. Http:www.orpha.netdatapathoGBukBullousPemphigoid.pdf....

The specific dermatoses of pregnancy represent a heterogeneous group of pruritic skin diseases that have been recently reclassified and include pemphigoid (herpes) gestationis, polymorphic eruption of pregnancy (syn. pruritic urticarial papules and plaques of pregnancy), intrahepatic cholestasis of pregnancy, and atopic eruption of pregnancy. They are associated with severe pruritus that should...