how to cite this article: aghayan golkashani h, hatami h, farzan a, mohammadi hr, nilipour y, khoddami m, jadali f. tumors of the central nervous system: an 18-year retrospective review in a tertiary pediatric referral center. iran j child neurol. summer 2015;9(3):24-33.   abstract objective few studies exist on the demographics and trends of pediatric central nervous system (cns) tumors in ira...

OBJECTIVE Few studies exist on the demographics and trends of pediatric central nervous system (CNS) tumors in Iran. In this study, we retrospectively reviewed all cases with confirmed CNS tumors admitted to Mofid Pediatric Hospital, Tehran, Iran during the last 18 years. MATERIALS & METHODS Data on gender, age of diagnosis, pathologic classification and tumor location were extracted from the...

background: understanding the differences in genetics of malignancies is crucial for therapeutic decisions. this systematic review was conducted to evaluate the current evidence on genetics of bone tumors in the context of pediatric cancer. material and methods: we performed a systematic review of the literature published on genetics of pediatrics bone tumors, using pubmed, google scholar, scie...

Background: In this study, we examined the epidemiologic characteristics of childhood brain tumors in patients referred to MAHAK Pediatric Cancer Treatment and Research Center (one of the main national referral centers for childhood malignancies in Iran) for treatment. Materials and Methods: This cohort (simple sampling) study consisted of 198 children less than 15 year old with CNS tumor ref...

Background: spinal tumors constitute about 8 % of central nervous system tumors. They are not uncommon in pediatric population. Objectives: The author reviews his experience in surgical aspects and techniques of management of this subtype of pediatric tumors. Patients and Methods: Medical records of twenty five pediatric patients with spinal tumors admitted to Children's Cancer Hospital-Egypt (...

background: in this study, we examined the epidemiologic characteristics of childhood brain tumors in patients referred to mahak pediatric cancer treatment and research center (one of the main national referral centers for childhood malignancies in iran) for treatment. materials and methods: this cohort (simple sampling) study consisted of 198 children less than 15 year old with cns tumor refer...

Although significant advances have been made in treating malignant pediatric central nervous system tumors such as medulloblastoma, no effective therapy exists for diffuse pontine glioma or intramedullary spinal astrocytoma. Biology of these 2 tumors is poorly understood, in part because diffuse pontine gliomas are not treated surgically, and tumor specimens from intramedullary spinal astrocyto...

Introduction: Germ cell tumors account for 3.5 % of pediatric and yolk sac are the most common pure malignant germ in children. Testis ovary sites involvement children older than 2 years. Case Presentation: A 20-month-old boy with a complaint limping was described this case report. Abdominal ultrasonography showed 52 × 50 mm solid abdominal mass. pelvic computed tomography scans left paraspinal...

solitary plasmacytoma of bone is a rare malignant tumor mostly involving the axial skeleton. the tumor occurs in middle- aged or elderly people (mean age: 55 years) and has a high risk of progression to multiple myeloma. radiotherapy is the preferred treatment for this disease. we report a case of recurrent solitary plasmacytoma of the fourth lumbar vertebra in a 35-year-old male. the patient s...