background : children suffering from cancer always require pain relief and reduce anxiety when undergoing painful procedures. the aim of this study is to compare the effect of pethedine and ketamine administration in cancer-diagnosed children undergoing bone marrow aspiration and biopsy procedures. subjects and methods : a randomized, double-blinded, crossover trial was carried out on 57 childr...

background: pediatric patients on chemotherapy are vulnerable to invasive fungal infection especially candida spices. resistance to antifungal agents has increased in candida spp., especially in non-albicans species. this study aims to assess the susceptibility of candida spp. strains isolated from children with acute leukemia less than 18 years. materials and methods: this prospective cross-se...

abstract background: children suffering from cancer frequently use complementary and alternative medicine (cam). most of people do not disclose using cam to their physicians as they fear to be blamed or prohibited using them. some of these products may interfere with the conventional remedies. the aim of this study was to investigate the frequency and characteristics of cam use in pediatric onc...

how to cite this article: alavi s. paraneoplastic neurologic syndromes in children: a review article. iran j child neurol. 2013 summer; 7(3): 6- 14. objective paraneoplastic neurological syndromes (pns) were initially defined as neurological syndromes with unknown etiology that often associate with cancer. this broad definition may lead to misconception that any neurological syndrome, which coi...

Inflammation plays a critical role in the progression of cancer in children. On the other hand, children with cancer experience abnormal activation of the inflammatory system. Moreover, it is known that these patients have a predisposition to depression. According to studies, moderate to severe depression was observed in about 63% of children with cancer and acute illness. Therefore, identifyin...

abstract background totally implantable central venous access devices (ports) have been available for over 10 years, but have not been achieved widespread use in pediatric oncology patients. ports facilitate the administration of chemotherapy in children with cancer. materials and methods in this study, early complications of implantable central venous access devices in children with different ...

Abstract Background Totally implantable central venous access devices (ports) have been available for over 10 years, but have not been achieved widespread use in pediatric oncology patients. Ports facilitate the administration of chemotherapy in children with cancer. Materials and Methods In this study, early complications of implantable central venous access devices in children with diff...

The December 2004 Food and Drug Administration (FDA) approval of clofarabine (Clolar, Genzyme) for refractory pediatric acute lymphoblastic leukemia was a milestone in the history of pediatric cancer drug development. A rare occurrence, it represented approval of a new cancer drug for a pediatric cancer indication without prior approval for an adult cancer indication. This is a major exception,...

Since the American Academy of Pediatrics published guidelines for pediatric cancer centers in 1986 and 1997, significant changes in the delivery of health care have prompted a review of the role of tertiary medical centers in the care of pediatric patients. The potential effect of these changes on the treatment and survival rates of children with cancer led to this revision. The intent of this ...

The benefits of play-based occupational therapy for hospitalized children with cancer warrant further exploration. Pediatric cancer disease symptoms, complications from treatment, and multiple and prolonged hospitalizations restrict participation in the daily activities of a child’s life. However, occupational therapy services in pediatric oncology are limited because of the disease nature, tre...