background and objective: since there are very few studies on the immunodeficiency state of the iranian survivors of pediatric acute lymphoblastic leukemia (all), we conducted this study to determine the prevalence of humoral defects in children with all at least one year after completion of chemotherapy. methods: in this study, antibody titers for mumps, rubeola, rubella, tetanus and diphtheri...

background: acute lymphoblastic leukemia (all), the most common childhood cancer with a peak incidence in children from 2-5 years old, might be associated with poor prognosis and resistance to therapy in specific cytogenetic backgrounds. foxo3a, a member of the forkhead class 'o' (foxo) transcription factors, is a main downstream target of pi3k/akt pathway which regulates different variety of b...

BACKGROUND Socioeconomic inequalities in obesity are consistently observed in high-income countries. The development of such inequalities across childhood; however, has not been studied using longitudinal data. METHODS Using data from the Avon Longitudinal Study of Parents and Children (participants were born 1991/2 in South-West England), we modelled trajectories of ponderal index (PI) (N=12...

STUDY OBJECTIVE To validate the Virtual Basic Laparoscopic Skill Trainer (VBLaST-PT; the peg transfer task) for concurrent validity based on its ability to differentiate between novice, intermediate, and expert groups of gynecologists, and the gynecologists' subjective preference between the physical Fundamentals of Laparoscopic Surgery (FLS) system and the virtual reality system. DESIGN Pros...

Parents frequently bring their children to general or pediatric emergency departments (EDs), even though many of these visits are judged by others to be "nonurgent" and inappropriate. This study examined the motives behind parents' decisions to take their children to a pediatric emergency department (PED). At a PED in Toulouse, France, 497 parents rated their level of agreement with each of 69 ...