نتایج جستجو برای: pederine

تعداد نتایج: 8  

Journal: :The Journal of Cell Biology 1968
Agnese Brega Arturo Falaschi Luigi De Carli Mario Pavan

Pederine, a drug extracted from the coleopter Paederus fuscipes, inhibits the growth of in vitro cultured cell lines at concentrations of the order of 1.5 nanogram/ml. Cytological examination shows a generalized cytotoxic effect. Analysis of macromolecular syntheses by the use of radioactive precursors shows that pederine causes an almost immediate block of protein and DNA synthesis, without af...

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Journal: :Pediatric Research 1974

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Journal: :Journal of Cell Biology 1968

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Journal: :Archivos argentinos de pediatria 2013
Betina Pagotto Romina Plafnik Andrea Castillo Jimena Cionci María Eugenia Abad María Silvina Cabanilas Margarita Larralde

Paederus dermatitis is a peculiar contact dermatitis caused by pederine contained in the hemolimph of a small insect of the genus Paederus. It is characterized by vesico-pustulous eruption arising over an erythematous background, of sudden onset, over exposed areas of the body, and the history of outdoor activities. Diagnosis is based on the typical clinical features and the epidemiological con...

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Journal: :iranian journal of basic medical sciences 0
fariba samani cellular and molecular biology research center, babol university of medical sciences, babol, iran ali shabestani monfared cellular and molecular biology research center, babol university of medical sciences, babol, iran ebrahim zabihi cellular and molecular biology research center, babol university of medical sciences, babol, iran 2 department of pharmacology & physiology, school of medicine, babol university of medical sciences, babol, iran soraya khafri department of biostatistics, school of medicine, babol university of medical sciences, babol, iran maesoumeh karimi department of radiation therapy & oncology, shahid rajaei hospital, babolsar, iran haleh akhavan niaki cellular and molecular biology research center, babol university of medical sciences, babol, iran

objective(s):cervical cancer is a malignancy that is the second most common cause of death from cancer in women throughout the world. paederus beetle (paederus fuscipes) extract (pbe), contains bioactive compounds such as pederine which has cytotoxic properties and blocks dna and protein synthesis at very low concentrations. in this investigation we tried to determine the effects co-treatment w...

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2014
Fariba Samani Ali Shabestani Monfared Ebrahim Zabihi Soraya Khafri Maesoumeh Karimi Haleh Akhavan Niaki

OBJECTIVES Cervical cancer is a malignancy that is the second most common cause of death from cancer in women throughout the world. Paederus beetle (Paederus fuscipes) extract (PBE), contains bioactive compounds such as pederine which has cytotoxic properties and blocks DNA and protein synthesis at very low concentrations. In this investigation we tried to determine the effects co-treatment wit...

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Journal: :Cancer research 1970
F Mauro H Madoc-Jones

A number of cytotoxic drugs (mitotic poisons, chemical mutagens, bifunctional alkylating agents, inhibitors of DNA, RNA, or protein synthesis, for a total of 18 agents) have been tested for differences in their lethal effects through the generation cycle of HeLa and Chinese ham ster cells in culture. The patterns of age response of cells to each group of agents show some features in common: mit...

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Journal: Iranian Journal of Basic Medical Sciences 2014
Ali Shabestani Monfared Ebrahim Zabihi Fariba Samani Haleh Akhavan Niaki Maesoumeh Karimi Soraya Khafri

Objective(s):Cervical cancer is a malignancy that is the second most common cause of death from cancer in women throughout the world. Paederus beetle (Paederus fuscipes) extract (PBE), contains bioactive compounds such as pederine which has cytotoxic properties and blocks DNA and protein synthesis at very low concentrations. In this investigation we tried to determine the effects co-treatment w...

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