This study investigated the possible anti-inflammatory, analgesic, and antipyretic effects of ethanolic extract of Pedalium murex Linn. fruits in selected experimental animal models. Anti-inflammatory activity of Pedalium murex Linn., with doses of 200 mg/kg and 400 mg/kg, p.o., was evaluated by Lambda-carrageenan induced paw oedema in Wistar albino rats; analgesic activity with doses of 280 mg...

In the present study, stigmasterol has been reported from Pedalium murex L. of pedaliaceae family in vivo and in vitro. Quantification data revealed that the total sterol content was higher in callus than leaves. The in vitro studies showed that the maxmium amount of total sterol was found in 6 weeks old tissue and minimum in 2 weeks old callus culture. In vivo studies showed that higher conten...

Methods The ethyl acetate extract of Pedalium murex L., (250, 500, and 1000 mg/kg body weight) was administered orally to three groups of rats (five animals per group) in order to evaluate the activity of the extract against castor oil-induced diarrhea model in rat. Two other groups received normal saline (5mg/kg) and loperamide (5mg/kg) as positive control. The effect of the extract on intesti...

The aqueous and ethanolic extracts of Pedalium murex (Pedaliaceae) was investigated for antipyretic activity in rats using Brewer’s yeast-induced pyrexia models. Brewer’s yeast (15%) was used to induce pyrexia in rats. Both the extract (200 and 400 mg/kg body weight p.o produced a significant (p

The herbal vendors are the mobile tribal medicinement seen on the busy streets of many Indian cities selling crude medicinal plants and their products. They prescribe herbal treatment for several diseases, a skill they inherited from their forefathers through several generations of experience. They claim to have specific herbal remedies for the complete cure of some urino - genital disorders su...

the aqueous and ethanolic extracts of pedalium murex (pedaliaceae) was investigated for antipyretic activity in rats using brewer’s yeast-induced pyrexia models. brewer’s yeast (15%) was used to induce pyrexia in rats. both the extract (200 and 400 mg/kg body weight p.o produced a significant (p

OBJECTIVE To examine the antioxidant activity and total phenolic content of different solvent fractions of Pedalium murex (P. murex) Linn fruits (Family: Pedaliaceae) as well as the correlation between the total antioxidant capacity and total phenolic content. METHODS In the present study, the antioxidant activities of P. murex were evaluated using six in-vitro assays, namely total antioxidan...

The ethanolic fruit extract of Pedalium murex to ethylene glycol intoxicated rats reverted the levels of the liver and kidney markers to near normal levels protecting liver and renal tissues from damage and also prevents the crystal retention in tissues. The levels of ACP, ALP, AST, ALT in serum andurine were significantly increased due to the damaged structural integrity of renal and hepatic c...