studies suggest that children who start solid foods early are at risk for developing food allergies. herein, we evaluated the effects of the introduction of peanuts to the diets of children on emerging peanut allergies. children with allergic rhinitis and asthma were enrolled in the present study and evaluated in four stages. in the first stage, a clinical history was completed for all particip...

in december 2015, the world health organization (who) published the first ever report on the estimates of the global burden of foodborne diseases, which included diseases related to chemical exposures in foods such as peanut allergy. in the report, the burden of disease related to peanut allergies was measured for the european, american and west pacific regions. the report showed that unlike ot...

OBJECTIVES To observe the nature and frequency of adverse reactions caused by accidental peanut exposure in young children with clinical peanut hypersensitivity and to determine the value of serum peanut-specific IgE levels during follow-up. STUDY DESIGN Eighty-three children with clinical peanut hypersensitivity diagnosed before their fourth birthdays were contacted yearly to track adverse p...

Peanut allergy is a significant health problem because of the frequency, the potential severity, and the chronicity of the allergic sensitivity. Serum IgE from patients with documented peanut hypersensitivity reactions and a peanut cDNA expression library were used to identify clones that encode peanut allergens. One of the major peanut allergens, Ara h I, was selected from these clones using A...

Dendritic cells are believed to play an essential role in regulating the balance between immunogenic and tolerogenic responses to mucosal Ags by controlling T cell differentiation and activation via costimulatory and coinhibitory signals. The CD28/CTLA-4-CD80/CD86 signaling pathway appears to be one of the most important regulators of T cell responses but its exact role in responses to orally a...

Background Peanut butter is known as a healthy food . It is a type one hypersensitivity reaction to dietary substances from peanuts causing an overreaction of the immune system which in a small percentage of children may lead to severe physical symptoms. Peanut allergy is one of the most common causes of anaphylaxis, a pediatrics medical emergency that requires treatment with an epinephrine (ad...

PURPOSE Clinical features of peanut allergy can range from localized to systemic reactions. Because peanut and birch pollen have cross-reactivity, peanut can lead to localized allergic reaction in Fagales pollen-sensitized oral allergy syndrome (OAS) patients without peanut sensitization per se. The purpose of this study was to discriminate true peanut food allergy from cross-reactive hypersens...

Peanut and/or tree nut allergy is a major health concern affecting over 1% of Americans. Although food allergy in general is the most common cause of anaphylaxis treated in emergency departments, reactions to nuts account for a disproportionate amount of deaths from food allergy. Peanut allergy is a Type I hypersensitivity (IgE mediated) immune response. Eight peanut allergens have been identif...

Background Immediate hypersensitivity reactions to food are a major health concern for Canadians due to severity of reactions they elicit and their increasing prevalence. Currently 6% of children develop food allergy. Peanut (PN) hypersensitivity is one of the major causes of foodrelated anaphylaxis. We tested the hypothesis that the route of initial exposure to food antigen dictates the nature...

BACKGROUND It is well known that atopic dermatitis (AD) is related to food hypersensitivity, although its prevalence varies among several studies according to age group, severity, country, survey time, and test method. OBJECTIVE To examine the prevalence and status of food hypersensitivity among childhood AD patients in Korea. METHODS A total of 95 patients were enrolled in the study. The h...