نتایج جستجو برای: passive avoidance task

تعداد نتایج: 395193  

Journal: :basic and clinical neuroscience 0
abbas ali vafaei roghyeh pakdel saeed nikzad ali rashidy-pour

reconsolidation memory is defined as a process in which the retrieval of a previously consolidated memory returns to a labile state which is then subject to stabilization. previous studies have shown that mineralocorticoid receptors (mrs) modulate distinct phases of learning and memory, which display a high concentration and distinct distribution in the hippocampus. moreover, we found no studie...

Journal: :acta medica iranica 0
hamid sohanaki department of physiology, school of medicine, tehran university of medical sciences, tehran, iran. and department of physiology, school of medicine, iran university of medical sciences, tehran, iran. tourandokht baluchnejadmojarad department of physiology, school of medicine, iran university of medical sciences, tehran, iran. farnaz nikbakht department of physiology, school of medicine, iran university of medical sciences, tehran, iran. mehrdad roghani neurophysiology research center, shahed university, tehran, iran.

alzheimer’s disease (ad) is a disorder with multiple pathophysiological causes, destructive outcomes, and no available definitive cure. pelargonidin (pel), an anthocyanin derivative, is an estrogen receptor agonist with little estrogen side effects. this study was designed to assess pel memory enhancing effects on the a rat amyloid beta 25-35 (aβ) intrahippocampal microinjections model of ad in...

Journal: :iranian journal of basic medical sciences 0
kaveh tabrizian department of pharmacology and toxicology, faculty of pharmacy, zabol university of medical sciences, zabol, iran medicinal plants research center, zabol university of medical sciences, zabol, iran najmeh sadat yaghoobi department of pharmacology and toxicology, faculty of pharmacy, zabol university of medical sciences, zabol, iran mehrdad iranshahi biotechnology research center and school of pharmacy, mashhad university of medical sciences, mashhad, iran jafar shahraki department of pharmacology and toxicology, faculty of pharmacy, zabol university of medical sciences, zabol, iran ramin rezaee department of physiology and pharmacology, school of medicine, north khorasan university of medical sciences, bojnurd, iran

objective(s): auraptene (7-geranyloxycoumarin) (aur), from citrus species has shown anti-inflammatory, neuroprotective, and acetylcholinesterase (ache) and beta-secretase inhibitory effects. scopolamine is a nonselective muscarinic receptor antagonist which causes short-term memory impairments and is used for inducing animal model of alzheimer’s disease (ad). this research aimed to investigate ...

Jafar Shahraki, Kaveh Tabrizian Mahmoud Hashemzaei, Mehrdad Iranshahi Najmeh Sadat Yaghoobi Ramin Rezaee,

Objective(s): Auraptene (7-geranyloxycoumarin) (AUR), from Citrus species has shown anti-inflammatory, neuroprotective, and acetylcholinesterase (AChE) and beta-secretase inhibitory effects. Scopolamine is a nonselective muscarinic receptor antagonist which causes short-term memory impairments and is used for inducing animal model of Alzheimer’s disease (AD). This research aimed to investigate ...

Journal: :iranian journal of pharmaceutical research 0
f motamedi fg davoodi n naghdi

there are several conflicting evidences showing the effect of morphine on learning and memory processes. in the present study the effect of chronic morphine administration on passive avoidance, active avoidance and spatial learning and memory of morphine dependent male rats using passive avoidance shuttle box and morris water maze tasks were investigated, respectively. male rats received morphi...

Journal: :مجله علمی دانشگاه علوم پزشکی گرگان 0
معصومه اصل روستا asle-rousta m

background and objective: tamoxifen is one of the selective estrogen receptor modulators that exerts estrogen / anti-estrogen effects in various tissues. this study was done to evaluate the effect of chronic administration of tamoxifen on spatial memory and passive avoidance task in adult male wistar rats. methods: in this experimental study, 48 adult male wistar rats were randomly divided into...

Journal: :physiology and pharmacology 0
zeinab sharifkhodaei department of biology, science and research branch, islamic azad university, tehran, iran nasser naghdi department of physiology and pharmacology, pasteur institute of iran, tehran 13164, iran shahrbanoo oryan department of biology, tarbiat moalem university, tehran, iran parichehr yaghmaei department of biology, tarbiat moalem university, tehran, iran

introduction: neurohormones like testosterone and estradiol have an important role in learning and memory. the hippocampus is essentially involved in learning and memory, and is known to be a target for estradiol actions. estrogen receptors (ers) are highly expressed in ca1 of rat hippocampus, and mediate the effects of estrogen on learning and memory. estradiol receptor belong to a family of t...

Journal: :avicenna journal of neuro psycho physiology 0
ali nikkhah neurophysiology research center, hamadan university of medical sciences, hamadan, ir iran fatemeh ghahremanitamadon neurophysiology research center, hamadan university of medical sciences, hamadan, ir iran somayeh zargooshnia neurophysiology research center, hamadan university of medical sciences, hamadan, ir iran siamak shahidi neurophysiology research center, hamadan university of medical sciences, hamadan, ir iran sara soleimani asl neurophysiology research center, hamadan university of medical sciences, hamadan, ir iran; department of anatomy, hamadan university of medical sciences, hamadan, ir iran; neurophysiology research center, hamadan university of medical sciences, hamadan, ir iran, tel/fax: +98-8118380208

conclusions these data suggest that single bilateral microinjection of aβ (25-35) could impair memory and can be used as an ad model in wistar rats. results the results showed that aβ (25-35) significantly impaired both step-through latency and time in dark compartment in the passive avoidance task. background alzheimer's disease (ad) is the most common form of dementia that leads to neurotoxic...

F Motamedi FG Davoodi M Ghasemi N Naghdi

There are several conflicting evidences showing the effect of morphine on learning and memory processes. In the present study the effect of chronic morphine administration on passive avoidance, active avoidance and spatial learning and memory of morphine dependent male rats using Passive Avoidance shuttle box and Morris Water Maze tasks were investigated, respectively. Male rats received morphi...

F Motamedi FG Davoodi M Ghasemi N Naghdi

There are several conflicting evidences showing the effect of morphine on learning and memory processes. In the present study the effect of chronic morphine administration on passive avoidance, active avoidance and spatial learning and memory of morphine dependent male rats using Passive Avoidance shuttle box and Morris Water Maze tasks were investigated, respectively. Male rats received morphi...

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