The vision behind our project is a closed-loop system for continuous deep brain stimulation (DBS) based on features extracted from complex motion data. Our focus is on Parkinsons Disease (PD) patients, with a possible expansion to related neurological disorders. The system we envision is lightweight, will continuously gather motion information, will automatically extract high-level features fro...

objective: the present study was aimed to correlate the clinical tests with the laboratory measures under dual task conditions in parkinson's disease (pd). materials and methods: eleven people with idiopathic pd (modified hoehn and yahr scores 1-3) were selected by simple non-probability sampling. center of pressure (cop) data obtained by force platform was used to calculate mean total velocity...

Home based objective measures of bradykinesia and dyskinesia will be important in managing Parkinsons Disease (PD). The Aim of this paper was to further validate the Parkinsons Kinetigraph system as a tool for measuring bradykinesia and dyskinesia by examining its capacity capture the effect of therapeutic interventions, detect bradykinesia and asymmetry in a newly diagnosed patients, and corre...

Technology and target group: In Parkinsons disease, the brain cells that produce dopamine die. Approximately 15 000 patients in Sweden have Parkinsons disease. In its early stages, the disease can often be treated successfully by drugs. However, in most patients the disease progresses after a few years to a stage with complications where drugs no longer have a sufficient effect. In patients wit...

Apomorphine and certain ergot alkaloids (bromocriptine, lisuride and pergolide) have been available for several decades; for the last few years, they were joined by newer dopamine agonists (cabergoline, pramipexole and ropinirole) most of them are non-ergolines. Each of these dopamine agonists has its own pharmacological characteristics and occupies a place in the pharmacotherapy of Parkinsons ...

BACKGROUND Epidemiological data concerning the prevalence of major depression in PD patients in Belgium is very scarce. METHODS A total of 1086 patients with idiopathic Parkinsons disease were included in the analysis. The neurological evaluation of the patients was made by the Hoehn and Yahr Staging of Parkinsons disease, the Unified Parkinson Disease Rating Scale (UPDRS), and the Schwab and...