pancreatic neuroendocrine tumors (pnet) are uncommon pancreatic neoplasms, accounting for 1-2% of all pancreatic tumors. however, they have a better prognosis and long-term survival compared to exocrine pancreatic cancer. pnets can be divided into functional or non-functional based upon whether or not they excrete active substances relevant to specific clinical syndromes. skeletal muscle metast...

primary pancreatic leiomyosarcomas are rare malignant neoplasms with an aggressive course and a large size. a 56-year-old woman presented with an 8-year history of abdominal pain. multislice computed tomography revealed a large heterogeneous mass with necrotic, calcified and macroscopic fatty areas. the tumor was excised. histopathological evaluation revealed leiomyosarcoma of the pancreas. if ...

In infants and children, pancreatic neoplasms occur uncommonly. Histologically, these tumors can resemble pancreatic embryonic elements or more well-differentiated pancreatic structures, in a subset the cellular origin can’t be delineated. This review discusses three of the most classic pediatric pancreatic neoplasms: pancreatoblastoma, solid pseudopapillary neoplasms and pancreatic endocrine n...

context the current literature suggests that minimally invasive surgery is associated with faster recovery and less morbidity than open surgery. parenchyma-sparing pancreatectomy is minimally invasive surgery, including enucleation, inferior head pancreatectomy, spleen-preserving distal pancreatectomy, and central pancreatectomy, combined pancreatectomy such as inferior head pancreatectomy plus...

Pancreatic neuroendocrine neoplasms (PanNENs) are rare and heterogeneous diseases that account for less than 2% of all cases pancreatic cancer only 30% digestive neoplasia, even if their incidence prevalence continue to rise globally [...]

BACKGROUND Intraductal papillary mucinous neoplasms (IPMN) have been reported to be associated with concurrent, distinct pancreatic ductal adenocarcinoma (con-PDAC) in about 8% (range, 4-10%) of resected branch duct (BD) lesions. In addition, other pancreatic and ampullary tumors are occasionally diagnosed with IPMN in patients undergoing pancreatic surgery. The objective of this study is to de...

Background:Management guidelines for pancreatic intraductal papillary mucinous neoplasms (IPMN) andmucinous cystic neoplasms (MCN) are based on the assumption that mucinous cysts can be accurately distinguished from other pancreatic cystic lesions. Previous studies using surgical material have identified recurrent mutations in GNAS and KRAS in pancreatic mucinous neoplasms. Yet, the diagnostic ...

Pancreatic cancer is one of common malignant neoplasms. It characterized by poor prognosis and high mortality, which mainly due to detection in an advanced stage. This review presents epidemiological clinical characteristics pancreatic cancer, as well current strategies systemic treatment disease, including first- second-line chemotherapy, molecularly targeted therapies immunotherapy.