introduction : severepain is a major problem in patients with unresectable pancreatic cancer. the goal of this study is to evaluate the effects of thoracoscopic splanchnicectomy (ts) on pain control in these patients suffering from unresectable pancreatic cancer. methods:between years 2000 to 2011, 20 patients suffering from unresectable pancreatic cancer underwent ts due to severe pain. they w...

the purpose of this study was to evaluate the therapeutic result of ct -guided celiac plexus block for managing intractable upper abdominal pain due to pancreatic carcinoma or chronic pancreatitis. we treated 22 cancer patients who were on regular narcotic medication. after an iv infusion of 10mllkg ringer's lactate solution, all patients were rolled onto prone position, and lidocaine was ...

Introduction : Severepain is a major problem in patients with unresectable pancreatic cancer. The goal of this study is to evaluate the effects of Thoracoscopic Splanchnicectomy (TS) on pain control in these patients suffering from unresectable pancreatic cancer. Methods:Between years 2000 to 2011, 20 patients suffering from unresectable pancreatic cancer underwent TS due to severe pain. They w...

aim : the aim of this study was to assay the most common signs, symptoms, and positive paraclinical findings in pancreatic cancer. background : it seems that the most available method for early diagnosis of pancreatic cancer is using clinical history and especially appearance of early signs and symptoms. patients and methods : in this descriptive study, all pancreatic cancer patients referred t...

abstract autoimmune pancreatitis (aip) is a rare disorder that may be present as common bile duct stricture. the patient was a seventy-year-old man with presentations as recurrent abdominal pain and jaundice, elevated billirobin (bil) and elevated alkaline phosphatase (alkp) in association with the presence of hetrogenesity of the pancreatic head and dilated intra and extra hepatic bile ducts i...

Pain treatment is a critical aspect of pancreatic cancer patient clinical care. This study investigated the role of trypsin-protease activated receptor-2 (PAR-2) in pancreatic cancer pain. Pancreatic tissue samples were collected from pancreatic cancer (n=22) and control patients (n=22). Immunofluorescence analyses confirmed colocalization of PAR-2 and neuronal markers in pancreatic cancer tiss...

background: our knowledge regarding the epidemiology of pancreatobiliary cancers in iran is limited. this study presents the first population-based report on pancreatobiliary cancers performed in five provinces of iran. materials andmethods: data used in this study were retrieved from population-based cancer registries in five provinces of iran (gilan, mazandaran, golestan, ardabil and kerman) ...

There is emerging evidence on the mechanisms of pancreatic cancer pain. Following the establishment of an orthotropic transplantation model of pancreatic cancer, microarray analysis was performed to identify changes in the expression levels of pain‑associated genes in the spinal cord. A mouse model of pancreatic cancer‑induced pain was established by implanting SW 1990 cells into the pancreases...

pancreatic cancer (pc) is a progressive, fatal disease with a high degree of malignancy. more than 40000 peoplediefrom this cancer annually in the united states. as a multifactorial condition, pc has a complex nature, and there are several genes and signalingpathwaysimplicated in pc pathogenesis and progression. there are diffèrent mutations in master genesincludingtumorsuppressors and oncogene...

malignant tumors of pancreas are usually primary neoplasms and pancreatic metastases are rare findings. we are reporting a case of squamous cell carcinoma (scc) of the esophagus with pancreatic metastasis. a 59-year old woman was admitted with chief complaint of abdominal pain and mass. she was a known case of esophageal scc since 4 years before when she had undergone transthoracic esophagectom...