objective: the study assessed the efficacy of low dose ketoconazole in addition to clomiphene citrate ( cc) and hmg on ovulation induction. materials and methods: a double blind, randomized, clinical trial was performed on fifty infertile patients with pcos who had failed to respond to a daily dose of hmg and 100 mg cc for controlled ovarian hyperstimulation in vali-e-asr reproductive health re...

BACKGROUND While menopause results in the loss of cyclic steroid production, evidence exists for persistent, albeit reduced, ovarian androgen production. In order to continue to synthesize ovarian androgens, the steroidogenic enzymes necessary for androgen biosynthesis must be present. Few studies have selectively analysed some of the steroidogenic enzymes present in the post-menopausal ovary (...

background and objectives: presence of steroid hormone receptors (estrogen and progesterone) in the tumor tissues of various organs correlates with response to therapy and prognosis. since their role in ovarian cancer is still controversial, in this study we investigated the expression and prognostic value of the estrogen receptor (er) and progesterone receptors (pr) in ovarian papillary serous...

Ovarian tissue banking is a developing technique aimed to preserve fertility in women at risk for premature ovarian failure (1–3). It entails cryopreservation of ovarian tissue with the option of autografting. Reports on the autografting of cryopreserved ovarian cortex segments describe the resumption of steroid production (4), follicle development (5, 6), and (in sheep) model successful pregna...

  Background and Objectives: Presence of steroid hormone receptors (estrogen and progesterone) in the tumor tissues of various organs correlates with response to therapy and prognosis. Since their role in ovarian cancer is still controversial, in this study we investigated the expression and prognostic value of the estrogen receptor (ER) and progesterone receptors (PR) in ovarian papillary ser...

to study the effect of dietary animal and plant lipids on gonadal differents and sex steroid hormones levels of blood in rainbow trout (oncorhynchus mykiss), the four diets was formulated based on 15% fat. the control uses 100% oil, fish oil was treated in the first, second and third respectively 25% and 75% fish oil, soybean oil, canola and cotton were used. after six weeks of feeding fish wit...

The influence of high density lipoproteins (HDL) on luteinizing hormone-stimulated rat ovarian theca/interstitial cell steroidogenesis was studied. Without HDL the cells produced primarily androgens from progestin precursors. In the presence of rat or human HDL steroid output increased 3-5-fold, but the type of steroid produced was dependent on the source of the HDL. Human HDL nonselectively am...

in order to determine the most effective hormones on the in vitro oocyte maturation (germinal vesicle breakdown - gvbd) in a hybrid sturgeon bester, ovarian follicles were incubated at the migratory nucleus stage in the presence of several steroids, gonadotropin preparations and forskolin. occurrence of gvbd and 17,20β-dihydroxy-4-pregnen-3 -one (dhp) production were followed during an expe...