background: previous studies have reported the antifertility activities of sulfonamides. this study was designed to evaluate the effects of co-trimoxazole and its co-administration with folic acid on ovarian tissue in female rats. methods: a total of 54 rats were randomly divided into 9 groups (n=6) . group i served as the control and group ii (vehicle) received saline. other groups, iii to ix,...

background: ovarian tissue transplantation is emerging technologies for fertility preservation. in addition, in vitro maturation (ivm) of oocytes retrieved from ovarian tissues may overcome the fertility defects in certain cases. objective: the aim was to evaluate the best site for ovarian tissue transplantation in mice. also, feasibility of ivm of oocytes retrieved from auto grafted ovarian ti...

the majority of cancer treatments are invasive. gonadal injuries cause reductions in fertility which results in lack of hope for conception in cancer patients and frustration for their partners. fortunately, current advancements in cryopreservation and transplantation sciences regarding fertility preservation lead to cryostorage of gonads and preservation prior to the onset of chemo- and radiot...

A method is presented to quantitatively score the degree of ovarian maturation in a predacious pentatomid with asynchronous follicle development. The effects of artiÞcial diet and mating status on ovarian maturation rates were examined. Ovarian scores were not inßuenced by mating status but were signiÞcantly lower in females fed the artiÞcial diet. Ovarian follicles start forming when females a...

Background: Previous studies have reported the antifertility activities of sulfonamides. This study was designed to evaluate the effects of co-trimoxazole and its co-administration with folic acid on ovarian tissue in female rats.Methods: A total of 54 rats were randomly divided into 9 groups (n=6). Group I served as the control and group II (vehicle) received saline. Other groups, III to IX, r...

Background: Immaturity of the ovarian follicles results in an infertility citation called Premature Ovarian Failure (POF), affecting approximately 1% of women under the age of 40. Women with this disorder go through early menopause and have high levels of gonadotropin hormones (FSH & LH). Diminished Ovarian Reserve (DOR) is another infertility disorder in which women’s ovaries have the ability ...

background: repeated in vitro fertilization (ivf) failure together with ovarian hyperstimulation syndrome (ohss) is one of the distressing situations leading couples to search for alternative treatment options. for such patients with polycystic ovarian syndrome (pcos) who have experienced ovarian hyperstimulation syndrome, mild ovarian stimulation with in vitro oocyte maturation could be a prom...

Background: This study was set up to evaluate the effect of ovarian tissue slow freezing on in vitro growth and pattern of maturation genes expression in mouse preantral follicles encapsulated within alginate hydrogel. Materials and Methods: Ovaries of 12-14 days old female NMRI mice were randomly allocated into control and slow freezing groups. In slow freezing group, ovaries were equilibrated...

Background: In vitro culture of ovarian follicles may preserve fertility in women with premature ovarian failure due to cancer .It seems that creation a condition that could maintain cellular communications and supports growth of follicles to produce mature oocytes appear to be essential. Nitric oxide (NO) has been recently shown to act with a dual action in mouse oocyte meiotic maturation depe...

Background: Ovarian tissue cryopreservation and autotransplantation is the only fertility preservation way for prepubertal girls and situations that cytotoxic treatment is urgent. Materials and Methods: The ovaries of premature (5 weeks old) rats were autografted under cervical skin after vitrification. 3 weeks later, transplanted ovaries were removed from the body and structure of ovary, expre...