IMPORTANCE OF THE STUDY. Currently, there is a paucity of evidence in the literature to show that handoff strategies improve the quality of handoff outcomes. Studies that show the usefulness and outcomes obtained from sign-outs may motivate junior clinicians, who have limited time to perform their clinical responsibilities, to support sign-out improvement efforts. OBJECTIVE. To test a research ...

Expansions of CTG/CAG trinucleotide repeats, thought to involve slipped DNAs at the repeats, cause numerous diseases including myotonic dystrophy and Huntington's disease. By unknown mechanisms, further repeat expansions in transgenic mice carrying expanded CTG/CAG tracts require the mismatch repair (MMR) proteins MSH2 and MSH3, forming the MutSbeta complex. Using an in vitro repair assay, we i...

BACKGROUND To evaluate the type and frequency of antiretroviral drug stock-outs, and their impact on death and interruption in care among HIV-infected patients in Abidjan, Côte d'Ivoire. METHODS AND FINDINGS We conducted a cohort study of patients who initiated combination antiretroviral therapy (cART) in three adult HIV clinics between February 1, 2006 and June 1, 2007. Follow-up ended on Fe...

In the present study, drop-out-analyses were carried out for a manual-based cognitive-behavioral therapy for 104 females with anorexia nervosa (AN) and bulimia nervosa (BN), in the service setting of a university outpatient clinic (naturalistic setting). A total of 22.9% of patients with AN terminated therapy prematurely (drop-outs), compared to 40.6% of patients with BN. Group differences betw...

Use of composites for a range of structural application in aircrafts, space-crafts, automobiles, etc., has widely spread in the last few years. Other than weight reduction, cut-outs provide pathways to link different aircraft parts. In this paper, an experimental investigation was conducted to study the effect of a cut-out on the tensile strength of the fiber glass/ epoxy composite plate. Geome...

constructing phase diagram and its subsequent quality lines for lean gas condensate reservoirs is always crucial and challenging topic in reservoir fluid studies. due to small amounts of liquid drop-outs in lean gas condensates at reservoir conditions, full experimental tracking of phase diagram and its relevant quality lines is almost impossible for lean gas condensates.on the other hand, eos ...

Secretion of pectate lyases and a cellulase occurs in Erwinia chrysanthemi through a type II secretion machinery, the Out system. Proper insertion of the secretin OutD in the outer membrane requires the presence of OutS. OutS is an outer-membrane lipoprotein that interacts directly with OutD. Using ligand-blotting experiments, it has been shown that this interaction requires at least the 62 C-t...

In this paper we consider one of the classical finite state machine (FSM) model modifications FSM with time-outs (or timed FSM). In this model in addition to the ordinary transitions under inputs there are transitions under time-outs when no input is applying. The behavior of many modern systems includes time-outs, for example, mobile phones, etc. In the past few years some work have been carri...