BACKGROUND The sudden appearance of acanthosis nigricans on the skin of an individual is highly suggestive of an underlying clinical disease. However, there is no information on its possible association with head and neck disease in our environment. OBJECTIVE To determine the prevalence of acanthosis nigricans and identifying the underlying associated medical and oncologic factor in an Otorhi...

BACKGROUND Randomised Controlled Trials (RCTs) are the preferred study design when comparing therapeutical interventions in medicine. To improve clarity, consistency and transparency of reporting RCTs, the Consolidated Standards of Reporting Trials (CONSORT) statement was developed. OBJECTIVES (1) To assess the quality of reports and abstracts of RCTs in otorhinolaryngologic literature by usi...

This review deals with concomitant diseases and risk factors in patients treated for otorhinolaryngologic disease in outpatient and hospital services. Besides heart disease, lung disease, liver disease and kidney disease this article also covers disorders of coagulation (including the therapy with new anticoagulant drugs) of electrolyte hemostasis. Special attention is paid to prophylaxis, diag...

Langerhans's cell histiocytosis (LCH) is an uncommon disease characterized by an accumulation of abnormal histiocytes, together lymphocytes and eosinophils in various organs and tissues. The head and neck are frequent sites of initial presentation. We present two cases of LCH with otorhinolaryngologic symptoms. Current recommendations for diagnosis, evaluation and treatment of LCH are also disc...

Sinusitis is a frequent otorhinolaryngologic disease, often misdiagnosed. None of the usual imaging equipment is specific, quick or efficient enough for sinusitis diagnosis. Misdiagnosis induces unnecessary health expenditures as well as a risk of antibiotic resistant strain development. Our study (with one healthy control subject, two pathological subjects) shows that infrared thermography cou...

Standardized olfactory tests are now available to quantitatively assess disorders of olfaction. A Brazilian-Portuguese version of the University of Pennsylvania Smell Identification Test (UPSIT) is currently being developed specifically for the Brazilian population. The most recent Brazilian-Portuguese version of the UPSIT (UPSIT-Br2) was administered to 88 Brazilian subjects who had no history...