We have investigated the effect of the insufficient autologous osteochondral graft on healing of the large articular cartilage defect using a rabbit model. An osteochondral defect, 7 mm in diameter, was made on the patellar groove of the femoral condyle and repaired with two surgical procedures: Group I, the osteochondral fragment as half as the defect was grafted. The graft was unstable and th...

In vivo osteochondral defect models predominantly consist of small animals, such as rabbits. Although they have an advantage of low cost and manageability, their joints are smaller and more easily healed compared with larger animals or humans. We hypothesized that osteochondral cores from large animals can be implanted subcutaneously in rats to create an ectopic osteochondral defect model for r...

PURPOSE To evaluate the treatment results of intraarticular injection according to the frequency of hyaluronic acid with mesenchymal stem cells on the osteochondral defect of rabbits' medial femoral condyles. MATERIALS AND METHODS A 5 mm diameter and 4 mm depth osteochondral defect was made on the medial femoral condyles of 18 rabbits, divided into six groups. One week after osteochondral def...

BACKGROUND Identifying factors associated with favorable or unfavorable outcomes would provide patients with accurate expectations of the arthroscopic marrow stimulation techniques. PURPOSE To investigate the prognostic significance and optimal measures of defect size in osteochondral lesion of the talus as treated with arthroscopy. HYPOTHESIS A critical, or threshold, defect size may exist...

Numerous procedures exist to treat osteochondritis dissecans (OCD); however, it remains a topic of debate which procedure is most ideal. When restoring a massive osteochondral defect, the use of only one procedure may not always allow complete filling of the defect. This case report presents a massive OCD with displaced osteochondral fragment and loose body in the knee joint that occupied almos...

The aim of the present study was to analyze cartilage repair tissue quality following synovial membrane‑derived mesenchymal stem cell (SMSC) transplantation in a rabbit osteochondral defect. A total of 15 New Zealand white rabbits were randomly distributed into three groups (n=5 in each group). In group 1, an osteochondral defect model was established in the right knee trochlea, prior to transp...

Introduction Articular cartilage is a highly specialised tissue which is organised into distinct layers that vary in both structure and composition according to distance from the surface. Cartilage has a poor ability to regenerate itself and as a result, superficial damage almost inevitably leads to the development of osteoarthritis (OA). Recently, the potential of osteochondral tissue engineer...

The objective of this study was to test the hypothesis that mechanical properties of artificial osteochondral constructs can be improved by a tissue-engineered zone of calcification (teZCC) at the bone-hydrogel interface. Experimental push-off tests were performed on osteochondral constructs with or without a teZCC. In parallel, a numerical model of the osteochondral defect treatment was develo...

PURPOSE To study the morphology of the articulation of the knee of rabbits after the repairing of the defect osteochondral standardized with resorcina adhesive or metallic synthesis. METHODS The procedure was to the creation of the defect osteochondral in femoral medial condylus of the knee of 80 rabbits, The animals were distributed in two groups with continuations of 7 and 42 days and submi...

The optimum management for recurrent glenohumeral instability with significant humeral head defects remains controversial. The purpose of this study was to compare outcomes and recurrence rates between patients who underwent osteochondral substitute grafting and patients who underwent remplissage to treat recurrent shoulder instability from an engaging Hill-Sachs defect with a Bankart lesion. T...