the association of obesity and other metabolic conditions with osteoarthritis is under debate; however, a strong link between metabolic disturbances is suggested to contribute to increased incidences and progression of osteoarthritis. we examined the association of metabolic syndrome and its components with the incidence of knee osteoarthritis in iranian population. a community-based study was ...

background:  new discoveries about the pathophysiology changed the concept that all forms of osteoarthritis are alike; this lead to the delineation of different phenotypes such as age, trauma or obese related forms. we aim to compare soluble mediator profiles in primary knee and posttraumatic wrist osteoarthritis. based on the general faster progression rate of wrist osteoarthritis, we hypothes...

background: traction has been suggested to be an effective treatment for symptoms of neck disorder in patients with no contraindications. however, according to previous researches, the effectiveness of traction is controversial, particularly compared to other conservative treatments. this trial was conducted to evaluate the effect of sustained traction, using an over-the-door home cervical trac...

introduction: knee joint osteoarthritis is one of the most prevalent musculoskeletal problems in adult population, which cause pain and functional limitations. involvement of medial compartment is almost 10 times more common than lateral compartment, which results in varus deformity among patients with medial compartment osteoarthritis of knee joint. main objectives in the treatment of knee joi...

knee osteoarthritis can have negative effects on the physical and mental conditions, social and family relations, general health and positive feelings of elders. for example, severe limitation of motion and increased depression, which are results of this disease, can have negative impacts on elders. the purpose of this study was to compare the levels of depression in healthy active and inactive...

background: knee osteoarthritis is a common degenerative joint disorder and a major cause of pain and disability. recent studies have suggested that bisphosphonates such as alendronate may have a role in the treatment of osteoarthritis. the purpose of the present study was to investigate the potential effect of alendronate on the symptoms of knee osteoarthritis.  methods: thirty nine patients w...

diagnosis of knee osteoarthritis can be confirmed based on clinical and/or radiological features. the potential of a progressive disease can be prevented or decreased by earlier recognition and correction of associated factors. obesity and alignment especially varus malalignment are recognized factors of a progressive disease. both nonpharmalogical as well as pharmacological modalities of treat...

objective(s): osteoarthritis (oa), as a known degenerative joint disease, is the most common form of arthritis. in this study, we aimed to elucidate unclear pathogenesis of oa. materials and methods: rabbit models of oa were established by the transection of the anterior cruciate ligament. rabbits were randomly divided into three equal groups: the experimental group (oa modeling, treated with e...