PURPOSE To our knowledge from indexed literature, the present study is the first one to systematically review the influence of local delivery of pamidronate (PAM) and/or ibandronate (IBA) on osseointegration enhancement. The aim of the present systematic review was to assess the efficacy of IBA and/or PAM local delivery (topically or coating on implants surfaces) in promoting osseointegration. ...

Dental implants are routinely used to treat edentulism. Their success depends on osseointegration, the direct functional and structural interlocking of implant and bone. The osseointegration mechanism is similar to bone remodeling and healing. Thus, chronic use of systemic medications that can interfere with bone turnover and healing may affect osseointegration, resulting in premature implant l...

i ntroduction: bisphosphonates are  widely used  for  various bone  diseases including osteoporosis and bone tumors. one of the complications associated with these pharmaceutical agents is bisphosphonate-related osteonecrosis of the jaw. this condition may be triggered by placement of dental implants. in turn,  osteonecrosis  of  the  jaw  may  cause  failure  in  osseointegration  of implants....

Hydroxyapatite coatings have been used on metallic substrates in a variety of applications, including modifying the surface of human implants, bone osseointegration and biological fixation. In this paper, the effects of various kinds of metallic substrate on clinical and pathological results of in vivo tests are presented. Four kinds of endodontic implants i.e, stainless steel, cobalt base all...

Hydroxyapatite coatings have been used on metallic substrates in a variety of applications, including modifying the surface of human implants, bone osseointegration and biological fixation. In this paper, the effects of various kinds of metallic substrate on clinical and pathological results of in vivo tests are presented. Four kinds of endodontic implants i.e, stainless steel, cobalt base all...

In year 2007, 30 years have elapsed since the first patient was supplied with a craniofacial osseointegrated implant. The reason for implanting in this patient was a severe conductive hearing loss, which necessitated the use of a bone conduction hearing aid. By utilizing the possibility to transmit sound to the cochlea via direct bone conduction, a new era in audiology was established. Further ...

T dental implants are synonymous with osseointegration. The concept of osseointegration and its clinical application have positively impacted dentistry and revolutionized the ability to reconstruct the dentition and the craniofacial complex. The ability of the surgeon to precisely place bone-anchoring devices to support prostheses via osseointegration has markedly influenced the approach to rec...

The purpose of this literature review is to collect the published data concerning factors affecting osseointegration. Popularity and large demand of dental implant makes this study essential because success of dental implant is directly related to the principle of osseointegration, a process of implant-bone interaction that finally leads to bone-implant anchorage. To identify relevant literatur...