background: major -thalassemia is the most common monogenic known disorder in iran and about 15000 persons are af fected. the purpose of this study was to evaluate the prevalence of orofacial complications. methods: in this cross-sectional study during 2003-2004, 300 patients with major -thalassemia referring to 8 hospitals for routine examinations, blood infusion and treatment in cities of teh...

PURPOSE Orofacial trauma is becoming a leading medical problem worldwide. Most of the studies pertaining to orofacial trauma have been done in urban areas but very little scientific literature is available for rural areas. METHODS A prospective medical institute-based study of orofacial injury patients was carried out from May 2013 to April 2016 (36 Months). Data regarding incidence, age and ...

This article reviews four of the involuntary hyperkinetic motor disorders that affect the orofacial region: bruxism, orofacial dystonia, oromandibular dyskinesia, and medication-induced extrapyramidal syndrome-dystonic reactions. It discusses and contrasts the clinical features and management strategies for spontaneous, primary, and drug-induced motor disorders in the orofacial region. The arti...

BACKGROUND Orofacial symptoms are common in Parkinson's disease (PD) both as initial manifestations and late markers of disease complications. We aimed to investigate the evolution of orofacial manifestations and their prognostic value throughout PD progression. METHODS Data was obtained from "Jönköping Parkinson Registry" database on routine care visits of 314 people with idiopathic PD in so...

Orofacial clefts are the commonest congenital structural anomalies of the lip and/or palate. Beyond cosmetic abnormality children often suffer from feeding difficulties, ear infections, hearing loss, speech and language delay, dental problems and multiple craniofacial/dental surgeries. Present study was conducted to assess DNA damage among children with orofacial clefts. One ml of peripheral bl...

Radiation therapy of the head and neck frequently results in serious and sometimes unavoidable changes to orofacial structures, particularly for children. Acute and chronic complications have a great impact on their oral function and quality of life. This paper provides an overview of the side effects of radiation therapy on children's oral and dental tissues, and highlights appropriate prevent...

Compromised health and hygiene can lead to many complications and one among them is traumatic wound myiasis. Myiasis is the invasion of living tissues by larvae of flies. Three cases of traumatic orofacial wound myiasis and treatment strategies followed for the management of them are reported in this paper.

BACKGROUND Reconstruction of orofacial soft tissue defects is often challenging due to functional and aesthetic demands. Despite advances in orofacial soft tissue defect reconstruction using free flaps, locoregional flaps still remain an important option, especially in health resource-depleted environments. This retrospective study highlights our experiences in oral and maxillofacial soft tissu...

Xeroderma pigmentosa (XP) is a condition inherited as an autosomal recessive trait and is characterized by photosensitivity, pigmentary changes, premature skin ageing and malignant tumour development resulting from the defect in DNA repair. The management of complications of XP, especially orofacial tumours entails an enormous surgical challenge to the clinicians. We present five cases of XP.