introduction: long-term levodopa treatment of parkinson’s disease (pd) is frequently complicated by spontaneously occurring involuntary muscle movements called dyskinesia. the exact pathological mechanism of this complication has not yet been elucidated. we have previously demonstrated that in pd patients the vulnerability to develop peripheral but not orofacial dyskinesia is associated with th...

In developed countries, orofacial pain is one condition in dentistry that has been well defined, explored, and managed. Unfortunately, unlike the grown and developed management of orofacial pain in developed countries, the management of orofacial pain in developing countries is still poorly performed. The current article discusses about the current management of orofacial pain in developing cou...

background: currently, orofacial sequelae are recognized as very influential on the qualityof- life for a victim of orofacial damage. therefore, correct forensic assessment for indenisation purposes is mandatory. however, orofacial damage is frequently reduced to organic components, which results in a forensic assessment process, which are inadequate. this study aims to improve the orofacial da...

Purpose: Orofacial function is the result of complex activities of the central nervous and neuromuscular systems. Orofacial dysfunction can compromise vital actions, such as breathing, chewing and swallowing, and facial expressions. The aim of this study was to apply the Brazilian version of the Nordic Orofacial Test–Screening (NOT-S), which assesses orofacial dysfunction, to a sample of Brazil...

Background Chronic orofacial pain conditions such as trigeminal neuropathic pain, reflex sympathetic dystrophy of the face, and temporomandibular pain disorders are debilitating pain conditions. They are known to respond poorly to treatment including opioids in human patients. There is a pressing need to better understand the mechanisms of these chronic orofacial pain conditions so that new and...

Orofacial granulomatosis (OFG) is a granulomatous disease of the orofacial region which appears usually as a persistent and/or recurrent labial soft tissue swelling in the orofacial region and is characterized histologically by a granulomatous inflammation. OFG may cause significant cosmetic and functional problems but can be prevented if the disease is diagnosed early and promptly treated. Thi...

The year 2013-2014 has been designated the Global Year Against Orofacial Pain by the International Association for the Study of Pain. Accordingly, a multidisciplinary Canadian and international group of clinical, research and knowledge-transfer experts attended a workshop in Montreal, Quebec. The workshop had two aims: to identify new pathways for innovative diagnosis and management of chronic ...

Pain in the oral and craniofacial system represents a major medical and social problem. Indeed, a U.S. Surgeon General’s report on orofacial health concludes that, ‘‘. . .oral health means much more than healthy teeth. It means being free of chronic oral-facial pain conditions. . .’’ [172]. Community-based surveys indicate that many subjects commonly report pain in the orofacial region, with es...

BACKGROUND Currently, orofacial sequelae are recognized as very influential on the quality-of-life for a victim of orofacial damage. Therefore, correct forensic assessment for indenisation purposes is mandatory. However, orofacial damage is frequently reduced to organic components, which results in a forensic assessment process, which are inadequate. This study aims to improve the orofacial dam...

Introduction: Long-term levodopa treatment of Parkinson’s disease (PD) is frequently complicated by spontaneously occurring involuntary muscle movements called dyskinesia. The exact pathological mechanism of this complication has not yet been elucidated. We have previously demonstrated that in PD patients the vulnerability to develop peripheral but not orofacial dyskinesia is associated w...