ornithine is a non-proteinogenic amino acid, which plays an essential role in the metabolism of plants. regard to the chirality of the molecule, physiological response of the plant cells to its two enantiomers have not been widely investigated yet. in the present study, suspension-cultured tobacco cells were treated with 1 mm of d- and lenantiomers of ornithine in normal conditions as well as u...

Ornithine is a non-proteinogenic amino acid, which plays an essential role in the metabolism of plants. Regard to the chirality of the molecule, physiological response of the plant cells to its two enantiomers have not been widely investigated yet. In the present study, suspension-cultured tobacco cells were treated with 1 mM of D- and Lenantiomers of ornithine in normal conditions as well as u...

Purpose of the study. The pharmacological effects ornithine are primarily due to its participation in neutralization ammonia and metabolism amino acids. To clarify mechanisms action ornithine, a chemoreactom analysis aspartate was performed comparison with S-ademetionine (S-AM) ursodeoxycholic acid (UDCA). Methods. investigated substances on urates (derivatives uric acid), vasoactivity, vascula...

Ornithine Trans Carboxylase Deficiency (OTCD) is a rare congenital genetic related disease.

In primary cultures of adult rat hepatocytes maintained in a salts/glucose medium, a more than 100-fold increase in ornithine decarboxylase (EC 4.1.1.17) activity was caused by asparagine and glucagon in a synergistic manner. The synthesis rate of ornithine decarboxylase was determined by [35S]methionine incorporation into the enzyme protein, and the amount of ornithine decarboxylase-mRNA was m...

Simultaneous administration of alpha-ketoglutarate and ornithine, in a 1:2 molar ratio, may improve the effectiveness of ornithine as an arginine precursor in neonatal piglets by shifting ornithine metabolism away from oxidation and toward the synthesis of arginine and other metabolically important compounds. To study this proposed mechanism, enterally fed piglets were allocated to receive 1 of...

We reviewed the literature on ornithine supplementation and related topics. Nutritionists and physicians have reported that ornithine supplementation is useful. Paediatricians and biochemists have reported that ornithine is supplemented for NH(3) detoxification in the hyperornithinaemia-hyperammonaemia-homocitrullinuria (HHH) syndrome. In contrast, ophthalmic researchers have reported retinotox...

In the kidney, L-ornithine is reabsorbed along the proximal convoluted tubule (PCT), transported by basolateral carriers, and produced by arginase II (AII). Here, the renal metabolic fate of L-ornithine was analyzed in male and female rats. Kidneys and renal zones were dissected and used for Western blot analysis, immunofluorescence, and electron microscopic studies. Ornithine aminotransferase ...

We reviewed the literature on ornithine supplementation and related topics. Nutritionists and physicians have reported that ornithine supplementation is useful. Paediatricians and biochemists have reported that ornithine is supplemented for NH3 detoxification in the hyperornithinaemia–hyperammonaemia–homocitrullinuria (HHH) syndrome. In contrast, ophthalmic researchers have reported retinotoxic...

Effects of L-ornithine (150 mg/l) on the germination, seedling growth, mitotic index, chromosome aberrations and micronucleus frequency Allium cepa L. bulbs germinated at 0.125 M salinity were studied. The radicle number group III in medium with ornithine alone as compared to ones I (control) which distilled water medium. But, their germination percentage, length fresh weight statistically same...