objective the extensive pollution of natural ecosystems has occurred by organophosphorus pesticides, being used for improvement of crop production in agriculture. biodegradation is interested in application of multifunctional bacteria containing genetical elements which specially degrade organophosphorus compounds. in this paper the detection of two bacteria species, pseudomonas and flavobacter...

Objective The extensive pollution of natural ecosystems has occurred by organophosphorus pesticides, being used for improvement of crop production in agriculture. Biodegradation is interested in application of multifunctional bacteria containing genetical elements which specially degrade organophosphorus compounds. In this paper the detection of two bacteria species, Pseudomonas and Flavobacte...

Enzyme-based Detoxification of Organophosphorus Neurotoxic Pesticides and Chemical Warfare Agents. (December 2007) Rory James Kern, B.S., Texas A&M University Chair of Advisory Committee: Dr. James Wild There are some 15,000 known organophosphorus chemicals. Some of these OP’s, including VX and paraoxon, demonstrate an acute neurotoxicity due to the inhibition of cholinergic enzymes. Organophos...

continuous and excessive use of organophosphorus compounds has led to thecontamination of water and soil ecosystems. the degradation of organophosphorusinsecticides, chlorpyrifos, chlorpyrifos- methyl, cyanophos and malathion in mineral saltsmedia were studied. the effect of additional biofertilizers, singly or combined withorganic amendments, on chlorpyrifos and cyanophos degrading activity in...

Enzymes that are capable of degrading neurotoxic organophosphorus compounds are of increasing interest because of the lack of efficient and clean methods for their removal. Recently, a novel organophosphorus hydrolase belonging to the metallo-β-lactamase superfamily was identified and isolated from the mesophilic bacterium Pseudomonas pseudoalcaligenes. This enzyme, named OPHC2, is endowed with...

D9-Tetrahydrocannabinol (THC), the psychoactive ingredient of marijuana, has useful medicinal properties but also undesirable side effects. The brain receptor for THC, CB1, is also activated by the endogenous cannabinoids anandamide and 2-arachidonylglycerol (2-AG). Augmentation of endocannabinoid signaling by blockade of their metabolism may offer a more selective pharmacological approach comp...

Laboratory experiments investigated the comparative degradation of six organophosphorus insecticides in soil as affected by enhanced microbial degradation. The degradation rates and product distributions of chlorpyrifos, fonofos, ethoprop, terbufos, and phorate were not dramatically altered in soils containing microbial populations adapted to rapidly degrade isofenphos. An Arthrobacter sp. isol...

Pseudomonas stutzeri strain YC-YH1, isolated from pesticide-polluted soil, efficiently degrades organophosphorus pesticides (OPPs) such as chlorpyrifos, parathion-methyl, triazophos, and parathion. Here, we report the genome sequence (4.83 Mb) of P. stutzeri YC-YH1 to facilitate further investigation of the OPP-degrading mechanism.