Concentrations of polybrominated diphenyl ethers (PBDEs), and organochlorine pesticides (OCPs; DDTs, HCHs, CHLs, and HCB) were measured in human breast milk samples collected across Massachusetts, USA, in 2004. Seventeen PBDE congeners were found in the samples, ranging in concentration from 0.06 to 1910 ng g(-1) lipid wt. BDE-47 (2,2',4,4'-tetraBDE), BDE-99 (2,2',4,4',5-pentaBDE), and BDE-100 ...

Halogen bond has attracted a great deal of attention in the past years for hit-to-lead-to-candidate optimization aiming at improving drug-target binding affinity. In general, heavy organohalogens (i.e., organochlorines, organobromines, and organoiodines) are capable of forming halogen bonds while organofluorines are not. In order to explore the possible roles that halogen bonds could play beyon...

To date more than 3650 organohalogen compounds are known to be naturally produced by biogeochemical processes [1]. The current understanding of the abiotic formation of organohalogens during early diagenetic processes in soils and sediments are reviewed. Next to volatile alkyl halides and polar organohalogens such as haloacetates there is evidence that even semivolatile organohalogens (e.g. pol...

BACKGROUND Early puberty is a common worldwide problem. Different parameters as genetics, metabolic diseases, obesity, as well as environmental factors may affect the age of puberty. This systematic review aims to survey the related literature on the effects of environmental pollutants and especially organohalogens and phthalates on early puberty. MATERIALS AND METHODS A systematic review of ...

To investigate the relation between biological parameters, not earlier investigated in the polar bear, and organohalogen pollution in East Greenland polar bears, we initiated a sampling of adipose tissue, internal organs and skulls from more than 100 free-ranging polar bears killed by local subsistence hunters from Central East Greenland (69 ̊00’N to 74 ̊00’N) during 1999-2002. The present thesis...

Organohalogens, especially organochlorinated compounds (OCs) such as polychlorinated biphenyls (PCBs), have long been recognized as a potential threat to human health and, therefore, these compounds have been widely investigated in foods [3, 27], vegetation [9, 14], and the atmosphere [1, 11]. Recently, interest in using extractable organohalogens (EOX) as parameters for the quantification of t...

Concentrations of polybrominated diphenyl ethers (PBDEs), and organochlorine pesticides (OCPs; DDTs, HCHs, CHLs, and HCB) were measured in human breast milk samples collected across Massachusetts, USA, in 2004. Seventeen PBDE congeners were found in the samples, ranging in concentration from 0.06 to 1910 ng g À1 lipid wt. 0 ,6-pentaBDE) were the major congeners detected in breast milk samples. ...

Thousands of organohalogen compounds, including hazardous chemicals such as polychlorinated biphenyls (PCBs) and other persistent organic pollutants (POPs), were selectively and simultaneously detected and identified with simple, or no, purification from environmental sample extracts by using several advanced methods. The methods used were software extraction from two-dimensional gas chromatogr...

The pattern of organohalogens found in the marine environment is complex and includes compounds, only assignable to natural (chloromethane) or anthropogenic (hexachlorobenzene, PCBs) sources as well as compounds of a mixed origin (trichloromethane, halogenated methyl phenyl ether).The chemistry of the formation of natural organohalogens is summarized. The focus is put on volatile compounds carr...