نتایج جستجو برای: oral submucous fibroses

تعداد نتایج: 252914  

Journal: :dental research journal 0
t. v. p. sudha s. murali susan l. zunt lawrence i. goldblatt mythily srinivasan

background: keratinocyte growth factor (kgf) is a potent epithelial mitogen that acts by binding the kgf receptors (kgfrs) expressed on epithelial cells and regulates proliferation and differentiation. the objective of this study was to investigate the expression of kgf in the epithelium in oral precancer. materials and methods: archival tissues of oral submucous fibrosis (smf) and leukoplakia ...

Farzeen Tanwir, Humera Akhlaq

Oral submucous fibrosis is chronic progressive condition of oral cavity. The condition is well recognized for its malignant potential. Usually the disease initiates with redness, blistering, and ulceration inside the mouth. It is characterized by progressive fibrosis of submucosal tissue. The pathogenesis of oral submucous fibrosis is not well understood. Betelquid chewing is the major etiologi...

Journal: :iranian journal of pathology 2011
farzeen tanwir humera akhlaq

oral submucous fibrosis is chronic progressive condition of oral cavity. the condition is well recognized for its malignant potential. usually the disease initiates with redness, blistering, and ulceration inside the mouth. it is characterized by progressive fibrosis of submucosal tissue. the pathogenesis of oral submucous fibrosis is not well understood. betelquid chewing is the major etiologi...

Background and Objective: This study was aimed to evaluate the collagen fibers qualitatively and its correlation with microvascular density in various grades of oral submucous fibrosis (OSMF).   Material and Methods: The present study comprised of total 40 cases of oral submucous fibrosis. Picrosirius red staining was done on all the specimens’ sections. ...

2013
Xinchun Jian Xieshan Huang Deyu Liu Pu Xu Xiacheng Liu

To analyze the clinical symptoms and signs in cases of oral submucous fibrosis which has transformed into squamous cell carcinoma, twenty-nine patients with squamous cell carcinoma correlated with oral submucous fibrosis, leukoplakia, lichen planus were taken biopsy for positive diagnosis. The clinical and pathological diagnosis of oral submucous fibrosis depended on clinical and pathological d...

Journal: :Gut 1993
A G Phatak

Oral submucous fibrosis-a chronic disseminated intravascular coagulation syndrome with local coagulopathy EDITOR,-We have read the leading article in Gut with great interest. (Gut 1992; 33: 4-6). We were, however, disappointed as the work on oral submucous fibrosis published in Indian journals' and the American Journal of Clinical Patholog/ has not been covered by the authors. After working for...

2011
Koneru Anila Venkatesh G. Naikmasur

Objectives: To determine the frequency of micronucleated cells and micronuclei in oral submucous fibrosis patients and to compare with healthy individuals. Study design: Twenty patients with oral submucous fibrosis and twenty age-sex-matched healthy individuals as control group participated in this study. Exfoliated cells were obtained by scraping from right and left buccal mucosa and were scre...

2017
Deepa A G Bindu Janardanan-Nair Varun B R

Background Podoplanin is a type I transmembrane sialomucin-like glycoprotein that is specifically expressed in lymphatic endothelial cells. Studies have shown that assessment of podoplanin expression in the epithelial cells can be used to predict the malignant transformation of potentially malignant disorders and the metastatic tendency of primary head and neck squamous cell carcinoma. The aim ...

2016
Annette M Bhambal Navin Ingle Ajay Bhambal

Introduction: There has been a subtle yet steady augmentation in oral submucous fibrosis, a potentially malignant disorder, both in India and across the world. Various efforts are being made to develop dependable and non-invasive biochemical tests for the early detection and diagnosis of this disorder. Of late, the role of specific salivary biomarkers has been studied comprehensively. Methods: ...

2010
Siddharth Pundir Susmita Saxena Pooja Aggrawal

Oral submucous fibrosis (OSF) is a high risk precancerous condition characterized by changes in the connective tissue fibers of the lamina propria and deeper parts leading to stiffness of the mucosa and restricted mouth opening. Patients with severe cases have distinct difficulties in chewing, swallowing and speaking. It predominantly occurs in Indians and other population of the Indian subcont...

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