diabetes mellitus is accompanied with disturbances in learning, memory, and cognitive skills in the humans and experimental animals. due to the anti-diabetic and antioxidant activity of pelargonidin (pg), this research study was conducted to evaluate the efficacy of chronic oral pg on alleviating learning and memory disturbance in streptozotocin-diabetic rats. male wistar rats were divided into...

Recent reports have demonstrated various cardiovascular and neurological benefits associated with the consumption of foods rich in anthocyanidins. However, information regarding absorption, metabolism, and especially, tissue distribution are only beginning to accumulate. In the present study, we investigated the occurrence and the kinetics of various circulating pelargonidin metabolites, and we...

We examined the effects of anthocyanidins (cyanidin, delphinidin, malvidin, peonidin, petunidin, pelargonidin) on the aryl hydrocarbon receptor (AhR)-CYP1A1 signaling pathway in human hepatocytes, hepatic HepG2 and intestinal LS174T cancer cells. AhR-dependent reporter gene expression in transfected HepG2 cells was increased by pelargonidin in a concentration-dependent manner at 24h. Similarly,...

In this study, some quality changes in the optimally thermosonicated (59°C-455 J g-1) cloudy strawberry nectar during storage were evaluated and modelled. The of pH (3.40-3.78), residual polyphenol oxidase-(PPO) activity (24%-11%), total phenolic-(TP) content (688.7-543.2 mg L-1), monomeric anthocyanin-(TMA) (142.5-84.4 anthocyanin, colorless phenolic compounds analyzed three months at 4°C. sig...

Flower color is an important characteristic that determines the commercial value of ornamental plants. Gentian flowers occur in a limited range of colors because this species is not widely cultivated as a cut flower. Gentiana lutea L. var. aurantiaca (abbr, aurantiaca) is characterized by its orange flowers, but the specific pigments responsible for this coloration are unknown. We therefore inv...

The effect of cultivar and environmental variations their interaction on anthocyanin components strawberry were assessed for six cultivars grown in five locations from North to South Europe two different years. To evaluate the impact latitude- altitude-related factors, daily mean (Tmean), maximum (Tmax) minimum (Tmin) temperature global radiation accumulated 3, 5, 10 15 days before fruit sampli...

Strawberries contain many antioxidant phytochemicals such as vitamin C, carotenoids and phenolic compounds including anthocyanins (ACN). In the present study, antioxidant composition of fresh strawberries (FS) and stored strawberries (SS) and the bioavailability of the main strawberry bioactive compounds were determined in human subjects. Thirteen healthy volunteers consumed 300 g of FS and SS ...

The present study investigates the effect of strawberry antioxidants in beverage form on meal-induced postprandial inflammatory and insulin responses in human subjects. Overweight adults (n 24) consumed a high-carbohydrate, moderate-fat meal (HCFM) accompanied by either a strawberry or a placebo beverage in a cross-over design. Postprandial changes in plasma anthocyanins, their metabolites, ins...

Anthocyanins are colorful plant pigments with promising applications as pharmaceuticals and colorants. In order to engineer efficient pigment biosynthesis in Escherichia coli, the activities of various dihydroflavonol 4-reductases (DFRs) were characterized for the three primary dihydroflavonol substrates. The biochemical assays demonstrated variable DFR activities for dihydroflavonol with one B...